| HUMAN-TRIAL | evidence | Tirzepatide in Idiopathic Intracranial Hypertension Trial | Tirzepatide | human-rct · n = 60 | — |
| HUMAN-TRIAL | evidence | Effect of Tirzepatide on Brown Adipose Tissue in Obesity | Tirzepatide | Weight & fat loss · human-rct · n = 34 | — |
| HUMAN-TRIAL | evidence | Tirzepatide in Women With Obesity and Endometrial Intra-epithelial Neoplasia or Grade 1 Endometrial Cancer | Tirzepatide | human-rct · n = 40 | — |
| HUMAN-TRIAL | evidence | A Study of LY3841136 in Overweight and Obese Participants | Tirzepatide | Weight & fat loss · human-rct · n = 96 | — |
| HUMAN-TRIAL | evidence | A Study of Tirzepatide (LY3298176) in Healthy Participants and Participants With Type 2 Diabetes (T2DM) | LY-3298176 | Glycemic control · human-rct · n = 142 | — |
| HUMAN-TRIAL | evidence | CARTIZ Registry: Cartilage, Arthropathy and Imaging Under Tirzepatide in Zone-stratified Cohorts - A Four-Institute Mexican Observational Registry | Tirzepatide | Glycemic control · human-observational · n = 30 | — |
| HUMAN-TRIAL | evidence | A Study of Tirzepatide (LY3298176) in Chinese Participants Without Type 2 Diabetes Who Have Obesity or Overweight (SURMOUNT-CN) | LY-3298176 | Weight & fat loss · human-rct · n = 210 | — |
| HUMAN-TRIAL | evidence | Comparative Effectiveness of Two Initial Combination Therapies in Patients With Recent Onset Diabetes | Mounjaro | Glycemic control · human-rct · n = 256 | — |
| HUMAN-TRIAL | evidence | A Study of Tirzepatide (LY3298176) in Participants With Type 2 Diabetes on Metformin With or Without Sulfonylurea (SURPASS-AP-Combo) | LY-3298176 | Glycemic control · human-rct · n = 917 | — |
| HUMAN-TRIAL | evidence | Metabolic Interventions (Time-Restricted Eating, GLP1 Receptor Agonist, and Heart Healthy Diet) to Improve Cardiometabolic Health in Prostate Cancer Patients During Androgen Deprivation Therapy, IMPACT-ADT Trial | Tirzepatide | human-rct · n = 60 | — |
| HUMAN-TRIAL | evidence | Tirzepatide for Weight Loss Intervention in Early-Stage Hormone Receptor Positive/HER2 Negative Breast Cancer | Mounjaro | n = 40 | — |
| HUMAN-TRIAL | evidence | A Study of Tirzepatide at Different Injection Sites in Participants With Different Body Sizes | LY-3298176 | human-rct · n = 54 | — |
| HUMAN-TRIAL | evidence | Mirikizumab and Tirzepatide Administered in Adult Participants With Moderately to Severely Active Crohn's Disease and Obesity or Overweight | LY-3298176 | Weight & fat loss · human-rct · n = 290 | — |
| HUMAN-TRIAL | evidence | A Study of Tirzepatide (LY3298176) Compared With Placebo in Adults With Type 1 Diabetes and Obesity or Overweight | LY-3298176 | Weight & fat loss · human-rct · n = 905 | — |
| HUMAN-TRIAL | evidence | Effects of Tirzepatide on Weight Loss and Chronic Inflammation in People With HIV | Tirzepatide | n = 12 | — |
| HUMAN-TRIAL | evidence | A Study of Tirzepatide (LY3298176) in Participants With Heart Failure With Preserved Ejection Fraction (HFpEF) and Obesity: The SUMMIT Trial | LY-3298176 | Weight & fat loss · human-rct · n = 731 | — |
| HUMAN-TRIAL | evidence | A Research Study to See How Well CagriSema Compared to Tirzepatide Helps People With Obesity Lose Weight | Tirzepatide | Weight & fat loss · human-rct · n = 809 | — |
| HUMAN-TRIAL | evidence | Tirzepatide for the Treatment of Cannabis Use Disorder | Tirzepatide | human-rct · n = 6 | — |
| HUMAN-TRIAL | evidence | Safety and Efficacy of NA-931 and Tirzepatide in Adults Who Are Overweight or Obese | Tirzepatide | Weight & fat loss · human-rct · n = 224 | — |
| HUMAN-TRIAL | evidence | Efficacy and Safety of Tirzepatide for Weight Management | Tirzepatide | Weight & fat loss · n = 440 | — |
| HUMAN-TRIAL | evidence | Clinical Study of Local and Systemic Biological Impact of GLP1/GIP-Receptor Agonists in Patients With Breast Cancer: The CLARA Trial | Tirzepatide | human-rct · n = 168 | — |
| HUMAN-TRIAL | evidence | Tirzepatide in the Treatment of Endometrial Cancer | Tirzepatide | n = 30 | — |
| HUMAN-TRIAL | evidence | Anti-obesity Pharmacotherapy and Inflammation | Mounjaro | Weight & fat loss · human-observational · n = 30 | — |
| HUMAN-TRIAL | evidence | A Study of Tirzepatide (LY3298176) in Chinese Participants With Type 2 Diabetes | LY-3298176 | Glycemic control · human-rct · n = 257 | — |
| HUMAN-TRIAL | evidence | Effectiveness and Safety of Tirzepatide Among Participants With Obesity With or Without Type 2 Diabetes Mellitus (T2DM) | Tirzepatide | Weight & fat loss · human-observational · n = 364 | — |
| HUMAN-TRIAL | evidence | Phase 1/2a Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics and Effect on Body Weight of RN3161 as Monotherapy and in Combination With Tirzepatide in Adults With Overweight and Obesity | Tirzepatide | Weight & fat loss · human-rct · n = 104 | — |
| HUMAN-TRIAL | evidence | Effect of Tirzepatide and Bimagrumab on Body Composition, Insulin Sensitivity, and Bone in Adults With Obesity | Tirzepatide | Weight & fat loss · human-rct · n = 63 | — |
| HUMAN-TRIAL | evidence | Combination of Biologic and Anti-obesity Therapies in Psoriatic Arthritis | Tirzepatide | Weight & fat loss · human-rct · n = 45 | — |
| HUMAN-TRIAL | evidence | Efficacy, Safety, and Treatment Satisfaction of Once-Weekly Tirzepatide in Obese Type 2 Diabetic Patients | Tirzepatide | human-rct · n = 52 | — |
| HUMAN-TRIAL | evidence | Tirzepatide to Reduce rEcurrence And Burden After Ablation of Atrial Fibrillation | Tirzepatide | Weight & fat loss · human-rct · n = 200 | — |
| HUMAN-TRIAL | evidence | Real-world Effectiveness and Dosing Patterns of Tirzepatide in People With Obesity | Mounjaro | Weight & fat loss · human-observational · n = 1700 | — |
| HUMAN-TRIAL | evidence | A Study of Tirzepatide (LY3298176) Compared to Dulaglutide in Participants With Type 2 Diabetes | LY-3298176 | Glycemic control · human-rct · n = 636 | — |
| HUMAN-TRIAL | evidence | Comparative Effectiveness of Tirzepatide Versus Semaglutide in Individuals With Heart Failure With Preserved Ejection Fraction | Tirzepatide | Glycemic control · human-observational · n = 28118 | — |
| HUMAN-TRIAL | evidence | Effect of Tirzepatide on Diabetic Peripheral Sensorimotor Neuropathy | Tirzepatide | human-rct · n = 40 | — |
| HUMAN-TRIAL | evidence | Evaluate the Efficacy of TIRZEPATIDE for the Treatment of Moderate to Severe HS Hidradenitis Suppurativa | Tirzepatide | n = 20 | — |
| HUMAN-TRIAL | evidence | Efficacy and Safety of Oral Azelaprag Plus Once Weekly Tirzepatide Compared with Tirzepatide Alone in Participants with Obesity Aged 55 Years and Over | Tirzepatide | Weight & fat loss · human-rct · n = 204 | — |
| HUMAN-TRIAL | evidence | A Research Study to See How Much CagriSema Lowers Blood Sugar and Body Weight Compared to Tirzepatide in People With Type 2 Diabetes Treated With Metformin, SGLT2 Inhibitor or Both | Tirzepatide | Glycemic control · human-rct · n = 1023 | — |
| HUMAN-TRIAL | evidence | Effects of Tirzepatide on Muscle and Vascular Health in Obese Older Adults | Zepbound | Weight & fat loss · n = 20 | — |
| HUMAN-TRIAL | evidence | Estimating the Impact of Obesity Medications on Clinical and Economic Outcomes | Zepbound | Weight & fat loss · human-observational · n = 125000 | — |
| HUMAN-TRIAL | evidence | Subcutaneous Tirzepatide Once-weekly in Patients With Obesity and Knee Osteoarthritis (STOP KNEE-OA) | Tirzepatide | Bone & joint health · human-rct · n = 352 | — |
| HUMAN-TRIAL | evidence | A Study to Measure Stomach Emptying in Overweight Non-diabetic and Diabetic Participants Using Tirzepatide | LY-3298176 | Weight & fat loss · n = 36 | — |
| HUMAN-TRIAL | evidence | Non-Invasive Hepatic and Metabolic Index Changes After Incretin Therapy in Overweight/Obesity | Mounjaro | Weight & fat loss · human-observational · n = 154 | — |
| HUMAN-TRIAL | evidence | Pathways, Risk Factors, and mOleculeS to Prevent Early-onset Colorectal Tumors | Zepbound | n = 20 | — |
| HUMAN-TRIAL | evidence | Pre-Surgical Tirzepatide-Assisted Weight Loss in Overweight and Obese Men With Intermediate Risk Prostate Cancer: A Pilot Feasibility Study | Tirzepatide | Glycemic control · n = 30 | — |
| HUMAN-TRIAL | evidence | Comparative Effectiveness of Tirzepatide Versus Sitagliptin in Individuals at Cardiovascular Risk (TIRZSITA-CVOT) | Tirzepatide | human-observational · n = 49065 | — |
| HUMAN-TRIAL | evidence | Effects of Tirzepatide on Blood, Imaging and Breast Tissue Biomarkers | Tirzepatide | Weight & fat loss · human-observational · n = 25 | — |
| HUMAN-TRIAL | evidence | A Study of Tirzepatide (LY3298176) Once a Week Versus Insulin Glargine Once a Day in Participants With Type 2 Diabetes and Increased Cardiovascular Risk | LY-3298176 | Glycemic control · human-rct · n = 2002 | — |
| HUMAN-TRIAL | evidence | Evaluation of Tirzepatide as an Adjunct to Buprenorphine for the Treatment of Opioid Use Disorder | Mounjaro | human-rct · n = 310 | — |
| HUMAN-TRIAL | evidence | A Randomized, Double-blind, Placebo-controlled Study Evaluating the Effect of LAE102 Injection in Combination With Tirzepatide on Body in Obese Participants | Tirzepatide | Weight & fat loss · human-rct · n = 60 | — |
| HUMAN-TRIAL | evidence | A Study of Tirzepatide (LY3298176) in Healthy Participants | LY-3298176 | human-rct · n = 52 | — |