| INDEPENDENT-REVIEW | review | How Joe Leveraged Tirzepatide, Macro Counting, and Resistance Training to Lose 18.1% of His Starting Weight in 19 Weeks
I love reading case studies showcasing the hard work and commitment of regular folks on a driven mission to improve their health and physiques, so I decided to make my own. (If you aren’t familiar, you can find real MacroFactor case studies here: | COMMUNITY | — | 2026-06-02 |
| INDEPENDENT-REVIEW | review | Nobody warned me that the hardest part of tirzepatide would be eating enough protein. Here's what actually worked.
[removed] | COMMUNITY | — | 2026-06-02 |
| INDEPENDENT-REVIEW | review | Tirzepatide
This is currently my 4 weeks old tirzepatide. Is it still safe to use? | COMMUNITY | — | 2026-06-01 |
| INDEPENDENT-REVIEW | review | 2.5mg Tirzepatide -When Did You Start Seeing Results?
Anyone else start seeing results on 2.5mg tirzepatide/Mounjaro? I know 2.5 is technically a starter dose, but I’ve read a lot of people still lose weight on it. I’m only a couple weeks in and definitely notice less food noise, but not a huge change on the scale yet.
How long did it take you to notice weight loss on 2.5? And did you stay on | COMMUNITY | — | 2026-05-28 |
| INDEPENDENT-REVIEW | review | [Stall Advice] SW: 106kg | CW: 86kg | GW: 82kg. Try pushing Tirzepatide higher, or introduce Retatrutide?
Hey everyone,
I’m looking for some advice on how to drop the last little bit of stubborn fat because I am completely stuck.
I started my fat loss journey on Mounjaro (Tirzepatide) at 106 kg (233 lbs) and titrated up very slowly. I was on 2.5 mg, stayed at 5 mg for a while, and eventually | COMMUNITY | — | 2026-05-26 |
| INDEPENDENT-REVIEW | review | Mounjaro / Tirzepatide Week 11 Update
[removed] | COMMUNITY | — | 2026-05-25 |
| INDEPENDENT-REVIEW | review | Lost significant muscle on tirzepatide
Photo 1 Left = before, right = after
Photo 2 Top = before, bottom = after
Photo 3 Top = before, bottom = after
Been on tirzepatide for 4 weeks and Reta for 1 week.
Went from 151-142lbs. Doesn’t matter what I eat I continue to lose weight, eating over 200g carbs a day, 160g protein and still resistance training 3-5 days a week with intensity.
It’s | COMMUNITY | — | 2026-05-24 |
| INDEPENDENT-REVIEW | review | I’m currently on tirzepatide can i stack with low dose of ret i need to lose a bunch of weight in about less than 2 months Can I stack tirzepatide and RET together
Lmk | COMMUNITY | — | 2026-05-24 |
| INDEPENDENT-REVIEW | review | 500 mg week test + tirzepatide
I'm pretty skinny fat guy
I'm 88 kgs at 172 cm with 61 kg of lean mass
I do wanna bump my muscle mass to 65 66 kg and body fat to 16 18 range with help of Anabolic test more than 500 mg test e or c with tirzepatide not reta as I'm only sticking with approved compounds
Please share your similar experience
I'm planning 2 months to start with tirzepatide and | COMMUNITY | — | 2026-05-24 |
| INDEPENDENT-REVIEW | review | Dancers using tirzepatide?
My girlfriend (mid 20s) recently moved from Europe to USA and is struggling greatly with food noise. We think due to the additives in US food. We have heard good things about micro-dosing tirzepatide to reduce food noise.
She wants to hear from a fellow ballet dancer that they have felt good in their bodies while using tirzepatide. She really trusts ballet dancers | COMMUNITY | — | 2026-05-22 |
| INDEPENDENT-REVIEW | review | VLS 20mg tirzepatide
Has anyone got any experience using this pen?
I purchased through a friend who had been using.
I want to know if anyone else has any experience with this pen?
I’ve verified it on the website. | COMMUNITY | — | 2026-05-21 |
| INDEPENDENT-REVIEW | review | Recurring GI Episodes on Tirzepatide
[removed] | COMMUNITY | — | 2026-05-21 |
| INDEPENDENT-REVIEW | review | Tirzepatide & Temps
I thought you might like to see this graph. The top section shows very little degradation over six months it kept cold. The bottom section shows more degradation if it's kept at 25°C, but it's not a lot. | COMMUNITY | — | 2026-05-20 |
| INDEPENDENT-REVIEW | review | Has anyone here gotten pregnant on tirzepatide/Zepbound while taking oral birth control
I’ve been on tirzepatide for almost a month now and I take oral birth control (Opill), I had no idea it lowers the effectiveness of birth control pills so now I’m feeling pretty worried. I did have sex recently and I’m due to ovulate at some point this week. I’m going to be a nervous wreck until my period | COMMUNITY | — | 2026-05-19 |
| INDEPENDENT-REVIEW | review | Is it a good 6 month progress considering the fact that i had already lost 25% of my body weight with semaglutide prior to tirzepatide?
With semaglutide 145kg->110kg (18 months)
With tirzepatide 110kg->98kg (7 months so far) | COMMUNITY | — | 2026-05-19 |
| INDEPENDENT-REVIEW | review | I have increased from 12.5 mg of tirzepatide to 15 mg
I have been on 12.5 for a few months, I didn’t want to increase it, mainly because of the financial cost that implies.
But I’ve been dealing with a sweets addiction for weeks that I can’t take anymore. So yesterday, it was my weekly dose, and I increased it to 15 mg and I don’t have any side effects. None.
Only that today, finally, I | COMMUNITY | — | 2026-05-19 |
| INDEPENDENT-REVIEW | review | Can you freeze compounded Tirzepatide vial?
My refrigerator is not functioning properly. I know I can freeze lyophilized tirzepatide.
Can I freeze compounded Tirzepatide and then thaw to use when needed? | COMMUNITY | — | 2026-05-15 |
| INDEPENDENT-REVIEW | review | Latest Surmount Study Findings on Tirzepatide Maintenance Presented Yesterday at the European Council on Obesity Conference Held in Istanbul
Presentation Synopsis:
[https://medicalxpress.com/news/2026-05-tirzepatide-full-dose-weight-loss.html](https://medicalxpress.com/news/2026-05-tirzepatide-full-dose-weight-loss.html)
Actual Study as posted in | COMMUNITY | — | 2026-05-14 |
| INDEPENDENT-REVIEW | review | Where can I buy Tirzepatide with B12?
What the title says :) | COMMUNITY | — | 2026-05-14 |
| INDEPENDENT-REVIEW | review | Question for the community: When it comes to Tirzepatide research, do you prefer 10mg or 15mg vials?
[removed] | COMMUNITY | — | 2026-05-12 |
| INDEPENDENT-REVIEW | review | Has anyone tried Tirzepatide and Retatutride? What were your comparisons?
[removed] | COMMUNITY | — | 2026-05-12 |
| INDEPENDENT-REVIEW | review | I hit my goal this week: down 35% from my high weight, the final 15 weeks w/ Tirzepatide. Insights into my learnings about food noise, tracking, protein, and avoiding negative side effects
Hi All!
This week I wrapped up a 15 week fat loss diet while using Tirzepatide, my first time ever doing so, and I learned some a few things along the way.
I’m not posting this as medical advice, nor as a | COMMUNITY | — | 2026-05-09 |
| INDEPENDENT-REVIEW | review | Tirzepatide first timer
My credentials
\- 5’7 5’8 female
\-145ish pounds obvs different on a daily due to water weight
\- lifting 4-5 days a week 3 leg days 1 upper
\-10-12k steps always
\- I work 12 hour shifts
\- meal prepaholic
\- eating 80% clean. Lil dirty bulk action just to force some calories in cuz I love burgers, cookies, icecream xoxo
I wanna start tirzepatide and I | COMMUNITY | — | 2026-05-07 |
| INDEPENDENT-REVIEW | review | Tirzepatide(Mounjaro) Labs - What This Drug Does To Your Body, Which Labs Catch What, And How To Actually Read Them
\## Mission Brief - What's Actually Happening Inside You
Tirzepatide activates two hormones your body already makes: GIP and GLP-1. These hormones tell your pancreas to release more insulin when blood sugar rises, and tell your liver to release less stored sugar between meals. The | COMMUNITY | — | 2026-05-07 |
| INDEPENDENT-REVIEW | review | Been on tirzepatide for 3 months and noticed this neck recently 🤦♂️
So I only lost around 15lbs in 3 months but I’m noticing this unsightly neck. It’s like vertical curtains that I can see in certain light. I never had that before with weight loss. I’m 6-3 and currently weigh 235lbs. How can I fix it? | COMMUNITY | — | 2026-05-06 |
| INDEPENDENT-REVIEW | review | would you take tirzepatide if you have no family medical history?
[removed] | COMMUNITY | — | 2026-05-06 |
| INDEPENDENT-REVIEW | review | Can I add Reta into my Tirzepatide regime
Hello all, ive been taking Tirz for 4 weeks now, gradully like this, 1.5mg > 1.95mg > 2.5mg> 3.75mg(this is where i started feeling heartburn at nights and probably insomnia, as well as a lot of energy) im currently down 22lbs id say im very disciplined at eating even before tirzepatide, im 6'5 33M, in case i want to add Reta how much should i start with? | COMMUNITY | — | 2026-05-06 |
| INDEPENDENT-REVIEW | review | Lost 92 lb’s on tirzepatide, need advice on peptides
28M 5.9 been overweight all my life
Current weight 167lb
2024 started on ozempic 260lb as pre diabetic (family members have diabetes) switched to mounjaro in early 2025 and started going to gym and boxing classes on August same year. Since gym+boxing lost 40 pounds but still have stubborn belly fat and skin on my waist area even with high | COMMUNITY | — | 2026-05-06 |
| INDEPENDENT-REVIEW | review | Desperately Searching for a Legit Tirzepatide Vendor
[removed] | COMMUNITY | — | 2026-05-06 |
| INDEPENDENT-REVIEW | review | Research proposal looking at whether your gut microbiome predicts how well you'll respond to tirzepatide / GLP-1 drugs
Most of us on this sub have noticed the wide range in how people respond to Mounjaro. Same dose, same titration schedule, very different HbA1c and weight loss outcomes.
A research group out of Hyderabad is proposing a study to ask whether baseline gut microbiome composition | COMMUNITY | — | 2026-05-06 |
| INDEPENDENT-REVIEW | review | A Synergistic Triad for Metabolic Health — Tirzepatide + MOTS-c + CoQ10 ... soliciting impressions, thoughts, opinions | COMMUNITY | — | 2026-05-05 |
| INDEPENDENT-REVIEW | review | Just started tirzepatide 2.5
Has anyone else gotten bad chest pains from acid coming up from stomach !! | COMMUNITY | — | 2026-05-04 |
| INDEPENDENT-REVIEW | review | Generic tirzepatide vs Mounjaro
[removed] | COMMUNITY | — | 2026-05-04 |
| INDEPENDENT-REVIEW | review | Key Differences of Retatrutide, Tirzepatide, Semaglutide & Mazdutide. | COMMUNITY | — | 2026-05-03 |
| INDEPENDENT-REVIEW | review | Tirzepatide
Hey guys. Has anyone used Tirzepatide to lose weight while they also have h pylori and bad gut issues?
I'm on the fence. Have about 140 to lose. So much inflammation. H pylori, gastritis, low hormones, iron deficient, pcos and more. I've been chronically ill and in pain for 6 years and think losing weight will help some things and heard it lowers inflammation. But I know it can also | COMMUNITY | — | 2026-05-03 |
| INDEPENDENT-REVIEW | review | Advice re tirzepatide
To start off with i am on week 2 so I know ive to give it time.
I am 26, im 176.5cm tall and my starting weight was 82.9kg and am now down a whopping kg.
I started on 2.5mg ,felt the food noise subside (I still count calories however) ,I then did 3mg this week on sunday night but I feel like the food noise is back this week and has been here all week. Nevertheless I | COMMUNITY | — | 2026-05-01 |
| INDEPENDENT-REVIEW | review | 3am tirzepatide stomach pains
I’ve been on mounjaro/tirzepatide for about 5 months and recently have been getting stomach pains at 3am that wake me out of my sleep and have me on the toilet letting out my whole life. It’s not every night. But when it does happen it’s always around 3am. And I always end up on the toilet. Does anyone else experience this ? I wonder if it is from eating something | COMMUNITY | — | 2026-05-01 |
| INDEPENDENT-REVIEW | review | Tirzepatide weight loss 80 lbs
Okay I wanted to share how far I’ve come with tirzepatide. I started in March 2025. I’ve gone from 220lbs to 140lbs. I have about 20lbs more to go to be where I want to be. It hasn’t been a steady decline either.
I was getting tirzepatide from a med spa near me initially from March through July 2025. But they stopped carrying it last year due to a court order with | COMMUNITY | — | 2026-05-01 |
| INDEPENDENT-REVIEW | review | 0 Day Peptide Stability Test Results: Mazdutide, Tirzepatide, and MOTS-C
[https://www.youtube.com/watch?v=lI4am0U49N4](https://www.youtube.com/watch?v=lI4am0U49N4) | COMMUNITY | — | 2026-04-30 |
| INDEPENDENT-REVIEW | review | Tirzepatide titration schedule feels arbitrary when current dose is still working
At 7.5mg, losing consistently, tolerating it well, no real side effects. My provider is nudging me toward 10mg at the next check-in just because it's been 4 weeks.
I get why the schedule exists. But if things are working and I'm not plateauing, I'm not sure I see the clinical reason to increase. Maybe I'm wrong | COMMUNITY | — | 2026-04-29 |
| INDEPENDENT-REVIEW | review | I think tirzepatide fixed my IBS. For years I've suffered every single day, until my first shot.
I don't even know how to explain this, but ive had many horrible effects over the last decade, and I've had to live with them
Magically, for the first time in over a decade, I feel like I have normal bathroom habits when I havent experienced this for a single day
I know its the glp because at the | COMMUNITY | — | 2026-04-27 |
| INDEPENDENT-REVIEW | review | Tirzepatide
Has anyone here from UK ordered a compounded tirzepatide from overseas and had no problem with UK customs? | COMMUNITY | — | 2026-04-27 |
| INDEPENDENT-REVIEW | review | Compounded tirzepatide
[removed] | COMMUNITY | — | 2026-04-27 |
| INDEPENDENT-REVIEW | review | Switching from Zepbound to Wegovy (or possibly compound tirzepatide) - experiences and advice
Hi all, I’m looking for feedback and real-world experiences from anyone who has transitioned medications or explored compound tirzepatide.
I’ve had a very good response to Zepbound and am currently on 12.5 mg, with 76 lbs lost overall. I still have about 30–40 lbs left to lose. The challenge is cost. I | COMMUNITY | — | 2026-04-27 |
| INDEPENDENT-REVIEW | review | How would I go about dosing retatrutide and Tirzepatide? I stalled out on Tirz and I'd like to incorporate Reta. I've seen comments about it not being effective, but if anyone has had any success with the combination, please share. TIA | COMMUNITY | — | 2026-04-27 |
| INDEPENDENT-REVIEW | review | Tirzepatide, Metformin, plus Ovasitol for PCOS results? | COMMUNITY | — | 2026-04-25 |
| INDEPENDENT-REVIEW | review | Never felt this weak on Tirzepatide (week 4 on 10mg)… is this normal?
Sharing where I’m at and see if anyone else has gone through something similar.
I started Tirzepatide back in Oct 2025 at 94.5kg, and just hit my goal weight of 75kg this week.
I’ve taken it slow the whole way — stayed on each dose as long as possible (except 2.5mg), and only moved up when weight loss stalled for a few weeks. | COMMUNITY | — | 2026-04-25 |
| INDEPENDENT-REVIEW | review | Tirzepatide vs Reta
Just wanting thoughts/opinions on them and which one you prefer? | COMMUNITY | — | 2026-04-24 |
| INDEPENDENT-REVIEW | review | Reta to Tirzepatide?
44 Male 240lbs
Been on 2.5 of Tirzepatide for 3 weeks
Thinking of starting Reta
I’ve never heard of stacking them and not planning to but just to get an answer, can you stack both?
Second question
I would start my 4th week of Tirzepatide this Sunday. Can I just stop Tirzepatide and immediately start Reta on Sunday instead?
Thanks in advance | COMMUNITY | — | 2026-04-24 |
| INDEPENDENT-REVIEW | review | Developing: New QUINTUPLE agonist GLP1 medication reportedly induced more weight loss than tirzepatide and retatrutide in animals | COMMUNITY | — | 2026-04-24 |