| INDEPENDENT-REVIEW | review | How much weight did you lose in your first 2 weeks on tirzepatide?
I’m almost 2 weeks in, and I’ve already lost more weight than I did over the last 2 years. It’s honestly more than I expected, and while I’m excited, it’s also made me a little concerned.
For context, I completely changed how I eat at the same time I started tirzepatide. I cut out junk food, added sugar, and highly processed | COMMUNITY | — | 2026-07-16 |
| INDEPENDENT-REVIEW | review | Zepbound (tirzepatide) induced anhedonia (the blahs or mehs)
Hey all! I know there were a lot of people asking about anhedonia in here. It's a part of depression but by itself without other depression symptoms it is its own thing. It's a lack of pleasure from doing things that were previously pleasureable.
I noticed this in quite a number of patients over the past few years and finally published | COMMUNITY | — | 2026-07-16 |
| INDEPENDENT-REVIEW | review | I've been on tirzepatide for 2 months and lost a grand total of 5lbs, am I being impatient, or is this a slow rate of weight loss?
So I noticed basically zero appetite change on the 2.5mg dose, but I did notice this vaguely nauseous sort of pressure / tickling in my throat. 5mg is where everything became a lot more noticeable. Every now and again I get a pronounced bout of nausea and my appetite | COMMUNITY | — | 2026-07-16 |
| INDEPENDENT-REVIEW | review | Switching from compounded tirzepatide
I am about to switch from compounded Tirz to branded Zepbound. At 15mg. I am not sure how the branded Zepbound will affect me, I.e, if it is stronger, likely to cause side effects, will the appetite suppression be greater. Can I get input from anyone who has made the transition, please? Thanks. | COMMUNITY | — | 2026-07-16 |
| INDEPENDENT-REVIEW | review | Why am I paying for tirzepatide when I could just buy the diarrhea lettuce?
That’s it, that’s the post. | COMMUNITY | — | 2026-07-15 |
| INDEPENDENT-REVIEW | review | Learn more about Tirzepatide
[removed] | COMMUNITY | — | 2026-07-14 |
| INDEPENDENT-REVIEW | review | Is anyone on tirzepatide (Zepbound) WITH metformin + spironolactone?
I’ve been on metformin for 2 1/2 years and it has helped me immensely to get regular periods and I’ve been regular for 1.5 years now! I’ve been on spironolactone for a year and it has helped me immensely with hair thinning.
My doctor knows I’m on those medication’s and she knows I wanna start Zepbound and she didn’t | COMMUNITY | — | 2026-07-13 |
| INDEPENDENT-REVIEW | review | Weight Plateau During Tirzepatide Therapy
I would like to share my clinical experience with **tirzepatide (Mounjaro)** and seek insights from others who may have encountered similar outcomes.
**Background:**
* Initiated therapy in **November 2025** at **2.5 mg weekly** for 1 month, then titrated sequentially:
* 5 mg for 1 month
* 7.5 mg for 2 months
* 10 mg for 1 month
* 12.5 mg | COMMUNITY | — | 2026-07-10 |
| INDEPENDENT-REVIEW | review | Nervous but excited Starting Tirzepatide today .
[removed] | COMMUNITY | — | 2026-07-08 |
| INDEPENDENT-REVIEW | review | Tirzepatide to Semaglutide
Hello fellow GLP1 friends. Please let me know if you have had to switch medications and how it went….
It will be 2 years on July 10th that I started Zepbound. I am down 75 pounds.
My insurance is no longer covering/ supplying Zepbound. They want to switch me to their preferred which is Wegovy.
I have been on 15mg since last May. Apparently Wegovy is not as | COMMUNITY | — | 2026-07-08 |
| INDEPENDENT-REVIEW | review | For HK residents considering tirzepatide (Mounjaro): what getting it prescribed in Shenzhen actually looks like
[removed] | COMMUNITY | — | 2026-07-07 |
| INDEPENDENT-REVIEW | review | How long it takes for to reset after tirzepatide use
Im curious if there are any studies or personal accounts of people reaching their goal weight and discontinuing medication and then resuming. Does the body’s sensitivity to the medication reset after some time? Or does the body just grow desensitized to the last dose and stay that way? Have there been any studies on this? | COMMUNITY | — | 2026-07-06 |
| INDEPENDENT-REVIEW | review | Restarting tirzepatide after pregnancy
Hi! Just wanted to share my experience.
I’ve been on GLP-1s for about 3 years now. They’ve honestly been life-changing for me…not just for weight loss, but they completely quiet my food noise, stopped my binge eating, helped my inflammation, and even improved my rosacea.
About a year ago I found out I was pregnant. As soon as I found out (around 5 | COMMUNITY | — | 2026-07-06 |
| INDEPENDENT-REVIEW | review | My father’s Tirzepatide efficiency denial
My dad (+60 M) has a couple of health conditions, some of which are chronic. Cardiac insufficiency/failure, sleep apnea, obesity being some of them.
Started him some months ago on Tirzepatide, after discussing it at length with our GP. First 2 months on 2.5mg, 3 months now on 5mg.
He obviously started to feel better, inflammation came down, his joints | COMMUNITY | — | 2026-07-05 |
| INDEPENDENT-REVIEW | review | Anyone stay on tirzepatide and stop the hair loss with oral minoxidil?
Basically the title. Looking to hear from anyone who successfully stayed on tirzepatide because oral minoxidil eventually stopped the hair loss.
Specifically, I’m looking to hear from people who had what seemed like drug-induced TE from tirzepatide, not hair loss from rapid weight loss.
My shedding started almost | COMMUNITY | — | 2026-07-04 |
| INDEPENDENT-REVIEW | review | I lost 70 pounds using compounded tirzepatide. After stopping it for a month, I gained 20 pounds, and I have no intention of repeating that experience. | COMMUNITY | — | 2026-07-04 |
| INDEPENDENT-REVIEW | review | Tirzepatide at Sea - Lost 80 Lbs
[removed] | COMMUNITY | — | 2026-07-03 |
| INDEPENDENT-REVIEW | review | 8 months on Tirzepatide, down 71 lbs, living on a cruise ship surrounded by buffets every day: here's what my labs actually showed
[removed] | COMMUNITY | — | 2026-07-03 |
| INDEPENDENT-REVIEW | review | Tirzepatide dose
Hi all, I started on Reta end of April got to 2.5 dose and my body couldn’t handle to side effects. I switched to tirzepatide started on 2.5 and currently in 5mg, this is my first week on 5mg, im thinking about going to a higher dose 7.5mg next week. Has anyone gone 5mg to 7mg without the 4 week period?
I’ve emailed my doctor for advice and waiting on a response. But just | COMMUNITY | — | 2026-07-03 |
| INDEPENDENT-REVIEW | review | Replacement for Tirzepatide and Additions | COMMUNITY | — | 2026-07-02 |
| INDEPENDENT-REVIEW | review | Continuing Tirzepatide Journey
Dress size before 2024 was 34/36 women's. Now in 2026, and finally below 300 pounds, I'm wearing a 24/26. Little snugly on the arms but I like the results. I'm no longer on Zepbound but taking Monjauro for continuing maintenance. | COMMUNITY | — | 2026-07-02 |
| INDEPENDENT-REVIEW | review | Microdosing Tirzepatide for addiction, not weight loss?
Haven't tried any GLP-1 yet, but looking into whether tirzepatide at 1mg/week helps with cravings/addiction — mainly kratom — rather than weight loss.
Has anyone here actually tried this for cravings? Did it help, or is that dose too low to feel anything? Any side effects worth knowing about before considering it?
For dosages like this, is | COMMUNITY | — | 2026-07-01 |
| INDEPENDENT-REVIEW | review | Insane Results out of Lilly’s Phase 1B Tirzepatide + Eloralintide Trial
Lilly has released preliminary Phase 1B data (via an abstract for EASD 2026) for Eloralintide + Tirzepatide. Big dropouts, probably due to the excessive pace, but also they may need to find the right titration schedule
▪️20.5% WL at 16 weeks on Tirzepatide 5mg + Elora 9mg (Study A cohort - 65% female)
▪️29% WL at 32 weeks | COMMUNITY | — | 2026-07-01 |
| INDEPENDENT-REVIEW | review | Does Mounjaro (tirzepatide) affect male fertility? Planning for a baby — washout period needed?
[removed] | COMMUNITY | — | 2026-07-01 |
| INDEPENDENT-REVIEW | review | Down 38 lbs on tirzepatide, got a DEXA scan and almost cried. Here's how much of it was muscle.
[removed] | COMMUNITY | — | 2026-07-01 |
| INDEPENDENT-REVIEW | review | Down 38 lbs on tirzepatide, got a DEXA scan and almost cried. Here's how much of it was muscle
I want to share this because nobody warned me and I wish someone had.
I started at 224. Eight months later I'm 186 and on paper that's a win. But I felt *weak*, like genuinely struggling-to-carry-groceries weak, so I paid for a DEXA scan to see what was actually going on.
Of the 38 lbs I lost, **about | COMMUNITY | — | 2026-07-01 |
| INDEPENDENT-REVIEW | review | Back on tirzepatide after a break, feeling really bad
On tirzepatide since September, first month 2.5 then always 5mg, never went up from then. Had some breaks for surgery, then came back.
The shot I did a week ago (5mg) was fine - only sulfur burps. The shot I did 2 days ago, same 5mg, has been awful. Two days of zero energy, can barely get out of bed, nauseous, constantly sleepy. I threw up | COMMUNITY | — | 2026-06-30 |
| INDEPENDENT-REVIEW | review | Tirzepatide Vs Semaglutide | COMMUNITY | — | 2026-06-29 |
| INDEPENDENT-REVIEW | review | Switching from compounded tirzepatide back to Zepbound. Side effects?
Has anyone switched from compounded tirzepatide back to Zepbound and noticed different side effects?
I started on Zepbound 2.5 mg, then used compounded tirzepatide (5 mg → 7.5 mg). Now I’m going back to Zepbound 7.5 mg after getting PA approved.
Just wondering if side effects hit differently when switching back or with dose | COMMUNITY | — | 2026-06-24 |
| INDEPENDENT-REVIEW | review | What worked for me and it was not tirzepatide, it was liraglutide.
[removed] | COMMUNITY | — | 2026-06-20 |
| INDEPENDENT-REVIEW | review | FDA vs GLP-1 (Tirzepatide, Semiglutide and Retatrutide)- Public Comments Needed Before June 10th
The FDA has a committee meeting to discuss banning anyone from making or compounding any type of GLP-1's. Which include Tirzepatide, Semiglutide and Retatrutide.
By law there is a public hearing that anyone can submit a comment.
**Deadline is June 29th**
Big pharma will have a their | COMMUNITY | — | 2026-06-19 |
| INDEPENDENT-REVIEW | review | Switching from tirzepatide to retatrutide. Need advice + what’s the best way to space out the weekly doses? Ideally, a dosing schedule for 119 kg —> 85–90 kg is the goal | COMMUNITY | — | 2026-06-19 |
| INDEPENDENT-REVIEW | review | Retatrutide is posting bariatric-surgery-level weight loss. But it scores lower on research quality than tirzepatide. At what point does chasing the more impressive result mean taking on more unknowns?
Been comparing compounds in the catalog and the tirzepatide vs retatrutide matchup is really interesting. Reta is the newer, more powerful drug, as the triple agonist successor to tirz, with | COMMUNITY | — | 2026-06-18 |
| INDEPENDENT-REVIEW | review | GLP fam - help me understand your preferences on Tirzepatide! | COMMUNITY | — | 2026-06-17 |
| INDEPENDENT-REVIEW | review | Id love to help everyone here save on their tirzepatide, brand name no measuring doses or wondering if its good quality
[removed] | COMMUNITY | — | 2026-06-16 |
| INDEPENDENT-REVIEW | review | What to do for Increase Muscle Mass ? My body fat is around 44%, and I currently weigh 266 lbs. I've been taking tirzepatide for about 3 months and have lost approximately 19 lbs so | COMMUNITY | — | 2026-06-16 |
| INDEPENDENT-REVIEW | review | Type 2 diagnosis + 20kg gained was my wake-up call. 10kg down in 2 months on tirzepatide — running, cycling and lifting in Barcelona, fighting to keep my muscle
A few months ago I got a type 2 diabetes diagnosis. I'd let things slide and put on about 20kg, and that was the kick I needed. I'm now on tirzepatide and two months in I'm down 10kg — slow and steady, and honestly obsessing over NOT | COMMUNITY | — | 2026-06-16 |
| INDEPENDENT-REVIEW | review | Is my diarrhea from the tirzepatide, or food poisoning (warning for TMI)
I've been on tirzepatide for 3 weeks now with my injections every Monday. Yesterday I ate:
​
Breakfast - 1 peach and a glass of metamucil
​
Work snack - mocha from coffee machine, egg mayo sandwich from tesco, apple grape and cheese snack pack from tesco, bottle of oasis (fruit drink)
​
Lunch - | COMMUNITY | — | 2026-06-11 |
| INDEPENDENT-REVIEW | review | Tirzepatide from China
was expecting to get 5mg but got 2.4mg at double volume.
(2.4ml 10mg and 2.4ml 20mg) | COMMUNITY | — | 2026-06-10 |
| INDEPENDENT-REVIEW | review | Tirzepatide in China.
was expecting to get 5mg but got 2.4mg at double volume.
(2.4ml 10mg and 2.4ml 20mg) | COMMUNITY | — | 2026-06-10 |
| INDEPENDENT-REVIEW | review | Tirzepatide
My DIL wants to buy the ingredients for tirzepatide, mix it herself and inject herself with it. Have you ever heard of anyone doing this? I think it’s extremely dangerous and foolish as no one’s house is a sterile environment. How does one know the things you are buying are legit? I have questions. | COMMUNITY | — | 2026-06-09 |
| INDEPENDENT-REVIEW | review | Is Zepbound more effective than compounded Tirzepatide?
I tried compounded and it is not as effective. The food noise is muchh stronger on name brand… but everyone swears its the same. Sigh | COMMUNITY | — | 2026-06-08 |
| INDEPENDENT-REVIEW | review | Pls, Need Advice on Restarting Tirzepatide After Hernia Repair
Hi everyone,
I’d like to get your opinion about restarting tirzepatide after a 2 weeks break.
I started taking tirzepatide on June 14, 2025, and since then I’ve lost about 35 kg (77 lbs) while staying on the 5 mg dose.
Recently, I had laparoscopic inguinal hernia repair surgery, and my surgeon instructed me to stop tirzepatide for | COMMUNITY | — | 2026-06-04 |
| INDEPENDENT-REVIEW | review | My idle dropped to a slow purr, first tirzepatide dose, 60 mins in. placebo? | COMMUNITY | — | 2026-06-04 |
| INDEPENDENT-REVIEW | review | Alguien conoce o ha utilizado Reta de laboratorio Synedica o Tirzepatide de Gluconex? Que resultados tuvieron?
[removed] | COMMUNITY | — | 2026-06-03 |
| INDEPENDENT-REVIEW | review | When to increase tirzepatide dose if you're still losing well at current level
​
At 5mg and losing about a pound a week consistently. No plateau, no side effects, feeling good. My provider mentioned moving to 7.5mg at the next check-in just because of where I am in the standard schedule.
If things are working, I'm not sure more is better here. But I also don't know what I don't know. | COMMUNITY | — | 2026-06-03 |
| INDEPENDENT-REVIEW | review | When to increase tirzepatide dose if you're still losing well at current level
At 5mg and losing about a pound a week consistently. No plateau, no side effects, feeling good. My provider mentioned moving to 7.5mg at the next check-in just because of where I am in the standard schedule.
If things are working, I'm not sure more is better here. But I also don't know what I don't know. | COMMUNITY | — | 2026-06-03 |
| INDEPENDENT-REVIEW | review | Lost 18.1% of my starting body weight in 19 weeks using Tirzepatide, macro tracking, and lifting
I wanted to share a breakdown of my most recent cut because I think it shows what worked for me beyond just “take the medication and eat less.”
From January 5th to May 17th, 2026, I lost 18.1% of my starting body weight. In scale weight, that was 156.1 lb down to 127.9 lb, or 28.2 lb total in just | COMMUNITY | — | 2026-06-02 |
| INDEPENDENT-REVIEW | review | Nobody warned me that the hardest part of tirzepatide would be eating enough protein. Here's what actually worked.
[removed] | COMMUNITY | — | 2026-06-02 |
| INDEPENDENT-REVIEW | review | Nobody warned me that the hardest part of tirzepatide would be eating enough protein. Here's what actually worked.
[removed] | COMMUNITY | — | 2026-06-02 |