| HUMAN-TRIAL | Tirzepatide vs Semaglutide in Individuals at Cardiovascular Risk But Without Diabetes. NCT07619508 · matched on "Tirzepatide" | human-observational | 100000 | not preregistered | — |
| HUMAN-TRIAL | Genetic predictors of GLP1 receptor agonist weight loss and side effects. PMID 41951734 · DOI 10.1038/s41586-026-10330-z · matched on "Tirzepatide" | human-observational | 27885 | none stated | 2026-05-01 |
| HUMAN-TRIAL | A Study of Tirzepatide (LY3298176) on the Reduction on Morbidity and Mortality in Adults With Obesity NCT05556512 · matched on "LY-3298176" | human-rct | 15374 | industry-funded | — |
| HUMAN-TRIAL | People With Lowest Physical Functioning Scores Showed Greatest Improvement After Tirzepatide Treatment. PMID 41187013 · DOI 10.1002/oby.70067 · matched on "Tirzepatide" | human-rct | 3788 | none stated | 2026-01-01 |
| HUMAN-TRIAL | A Study of Tirzepatide (LY3298176) Compared With Standard of Care in Adult Participants With Obesity and Without Diabetes (SURMOUNT-REAL UK) NCT07247084 · matched on "LY-3298176" | human-rct | 3000 | industry-funded, not blinded | — |
| HUMAN-TRIAL | A Study of Tirzepatide (LY3298176) in Participants With Obesity or Overweight NCT04184622 · matched on "LY-3298176" | human-rct | 2539 | industry-funded | — |
| HUMAN-TRIAL | GLP-1 Medication & Behavioral Health Programs on Weight & Metabolic Outcomes: FLOURISH and THRIVE Prospective Cohort Study NCT07588984 · matched on "Tirzepatide" | human-observational | 2310 | industry-funded | — |
| HUMAN-TRIAL | A Master Protocol Study (LY900038) of Multiple Intervention-Specific-Appendices (ISAs) in Adult Participants With Obesity or Overweight NCT06143956 · matched on "LY-3298176" | human-rct | 1481 | industry-funded | — |
| HUMAN-TRIAL | A Study of Tirzepatide (LY3298176) in Participants With Type 2 Diabetes Who Have Obesity or Are Overweight NCT04657003 · matched on "LY-3298176" | human-rct | 938 | industry-funded | — |
| HUMAN-TRIAL | A Study of Tirzepatide (LY3298176) Compared With Placebo in Adults With Type 1 Diabetes and Obesity or Overweight NCT06914895 · matched on "LY-3298176" | human-rct | 905 | industry-funded | — |
| HUMAN-TRIAL | A Research Study to See How Well CagriSema Compared to Tirzepatide Helps People With Obesity Lose Weight NCT06131437 · matched on "Tirzepatide" | human-rct | 809 | industry-funded, not blinded | — |
| HUMAN-TRIAL | A Study of Retatrutide (LY3437943) Compared to Tirzepatide (LY3298176) in Adults Who Have Obesity NCT06662383 · matched on "LY-3298176" | human-rct | 800 | industry-funded | — |
| HUMAN-TRIAL | A Study of Tirzepatide (LY3298176) in Participants With Obesity or Overweight for the Maintenance of Weight Loss NCT04660643 · matched on "LY-3298176" | human-rct | 783 | industry-funded | — |
| HUMAN-TRIAL | A Study of Tirzepatide (LY3298176) in Participants With Obesity or Overweight With Weight Related Comorbidities NCT05822830 · matched on "LY-3298176" | human-rct | 751 | industry-funded, not blinded | — |
| HUMAN-TRIAL | A Study of Tirzepatide (LY3298176) in Participants With Heart Failure With Preserved Ejection Fraction (HFpEF) and Obesity: The SUMMIT Trial NCT04847557 · matched on "LY-3298176" | human-rct | 731 | industry-funded | — |
| HUMAN-TRIAL | A Study of Tirzepatide (LY3298176) In Participants After A Lifestyle Weight Loss Program NCT04657016 · matched on "LY-3298176" | human-rct | 579 | industry-funded | — |
| HUMAN-TRIAL | A Long-Term Study of Tirzepatide (LY3298176) in Adults With Type 1 Diabetes and Obesity or Overweight NCT06962280 · matched on "LY-3298176" | human-rct | 465 | industry-funded | — |
| HUMAN-TRIAL | A Study of LY3298176 (Tirzepatide) For the Maintenance of Body Weight Reduction in Participants Who Have Obesity or Overweight With Weight-Related Comorbidities NCT06047548 · matched on "LY-3298176" | human-rct | 441 | industry-funded | — |
| HUMAN-TRIAL | Efficacy and Safety of Tirzepatide for Weight Management NCT06918405 · matched on "Tirzepatide" | not determined | 440 | not preregistered, not blinded | — |
| HUMAN-TRIAL | From awareness to action: evolving endocrinologist practices in obesity treatment in Italy. PMID 41244051 · DOI 10.3389/fendo.2025.1705670 · matched on "Tirzepatide" | human-observational | 424 | none stated | 2025-01-01 |
| HUMAN-TRIAL | AI-assisted Multi-domain Lifestyle Versus Tirzepatide for Weight Loss Maintenance in Adults With Type 2 Diabetes (AIM-MAINTAIN) NCT07555730 · matched on "Tirzepatide" | human-rct | 400 | not blinded | — |
| HUMAN-TRIAL | A Study of Tirzepatide (LY3298176) Plus Mibavademab Compared With Tirzepatide Alone in Adult Participants With Obesity NCT06373146 · matched on "LY-3298176" | human-rct | 392 | industry-funded | — |
| HUMAN-TRIAL | Efficacy and Safety of HDM1005 Compared to Tirzepatide in Obese Adults Without Diabetes NCT07521631 · matched on "Tirzepatide" | human-rct | 372 | industry-funded, not blinded | — |
| HUMAN-TRIAL | A Study to Investigate Weight Management With LY3841136 and Tirzepatide (LY3298176), Alone or in Combination, in Adult Participants With Obesity or Overweight With Type 2 Diabetes NCT06603571 · matched on "Tirzepatide" | human-rct | 367 | industry-funded | — |
| HUMAN-TRIAL | Effectiveness and Safety of Tirzepatide Among Participants With Obesity With or Without Type 2 Diabetes Mellitus (T2DM) NCT07099742 · matched on "Tirzepatide" | human-observational | 364 | industry-funded | — |
| HUMAN-TRIAL | A Research Study Comparing How Well Different Doses of the Medicine NN0519-0130 Help People With Excess Body Weight Lose Weight NCT06326060 · matched on "Tirzepatide" | human-rct | 354 | industry-funded | — |
| HUMAN-TRIAL | A Study of Tirzepatide (LY3298176) in Adult Participants in India With Either Type 2 Diabetes Mellitus or Obesity NCT07438444 · matched on "LY-3298176" | not determined | 344 | industry-funded, not blinded | — |
| HUMAN-TRIAL | Efficacy and Safety of GZR18 Every 2 Weeks Versus Tirzepatide and Placebo in Obese or Overweight Participants NCT06737042 · matched on "Tirzepatide" | human-rct | 326 | industry-funded | — |
| HUMAN-TRIAL | A Study of Tirzepatide in Adolescents With Obesity and Weight-Related Comorbidities (SURMOUNT-ADOLESCENTS-2) NCT06439277 · matched on "LY-3298176" | human-rct | 300 | industry-funded | — |
| HUMAN-TRIAL | Mirikizumab and Tirzepatide Administered in Adult Participants With Moderately to Severely Active Crohn's Disease and Obesity or Overweight NCT06937099 · matched on "LY-3298176" | human-rct | 290 | industry-funded | — |
| HUMAN-TRIAL | A Study to Assess Efficacy, Safety, Tolerability, Pharmacokinetics (PK) and Pharmacodynamics (PD) of RO7204239 in Combination With Tirzepatide in Participants With Obesity or Overweight With At Least One Weight-related Comorbidity NCT06965413 · matched on "Tirzepatide" | human-rct | 285 | industry-funded | — |
| HUMAN-TRIAL | Ixekizumab Concomitantly Administered With Tirzepatide in Adults With Moderate-to-Severe Plaque Psoriasis and Obesity or Overweight NCT06588283 · matched on "LY-3298176" | human-rct | 281 | industry-funded, not blinded | — |
| HUMAN-TRIAL | Ixekizumab Concomitantly Administered With Tirzepatide in Adults With Psoriatic Arthritis and Obesity or Overweight NCT06588296 · matched on "LY-3298176" | human-rct | 279 | industry-funded, not blinded | — |
| HUMAN-TRIAL | A Study of Tirzepatide (LY3298176) in Participants With Obesity Disease NCT04844918 · matched on "LY-3298176" | human-rct | 267 | industry-funded | — |
| HUMAN-TRIAL | Real-World Tirzepatide Therapy in Post-Bariatric Weight Regain and Preoperative Obesity Patients NCT07382180 · matched on "Tirzepatide" | human-observational | 254 | not preregistered | — |
| HUMAN-TRIAL | A Study to Investigate Weight Management With Bimagrumab (LY3985863) and Tirzepatide (LY3298176), Alone or in Combination, in Adults With Obesity or Overweight NCT06643728 · matched on "LY-3298176" | human-rct | 252 | industry-funded | — |
| HUMAN-TRIAL | Safety and Efficacy of NA-931 and Tirzepatide in Adults Who Are Overweight or Obese NCT06732245 · matched on "Tirzepatide" | human-rct | 224 | industry-funded | — |
| HUMAN-TRIAL | Precision Obesity Medicine: Genetic Prediction of Response to GLP-1/GIP Agonists. NCT07653412 · matched on "Tirzepatide" | human-observational | 220 | not preregistered | — |
| HUMAN-TRIAL | A Study of Tirzepatide (LY3298176) in Chinese Participants Without Type 2 Diabetes Who Have Obesity or Overweight (SURMOUNT-CN) NCT05024032 · matched on "LY-3298176" | human-rct | 210 | industry-funded | — |
| HUMAN-TRIAL | Efficacy and Safety of Oral Azelaprag Plus Once Weekly Tirzepatide Compared with Tirzepatide Alone in Participants with Obesity Aged 55 Years and Over NCT06515418 · matched on "Tirzepatide" | human-rct | 204 | industry-funded, not preregistered | — |
| HUMAN-TRIAL | A retrospective audit of weight loss and health outcomes following bariatric surgery at a tertiary public hospital. PMID 42142983 · DOI 10.1016/j.orcp.2026.05.003 · matched on "Tirzepatide" | human-observational | 203 | none stated | 2026-05-01 |
| HUMAN-TRIAL | A Study to Investigate the Effectiveness of Tirzepatide (LY3298176) Following Initiation of Ixekizumab (LY2439821) in Participants With Moderate-to-Severe Plaque PsO and Obesity or Overweight in Clinical Practice (TOGETHER AMPLIFY-PsO) NCT06857942 · matched on "LY-3298176" | not determined | 200 | industry-funded, not blinded | — |
| HUMAN-TRIAL | A Study to Investigate Effectiveness of Tirzepatide Following Initiation of Ixekizumab in Participants With Active Psoriatic Arthritis and Overweight or Obesity in Clinical Practice (TOGETHER AMPLIFY-PsA) NCT06864026 · matched on "LY-3298176" | not determined | 200 | industry-funded, not blinded | — |
| HUMAN-TRIAL | GLP-1 Therapy After Bariatric Surgery in Chinese Patients With Obesity NCT07633639 · matched on "Tirzepatide" | human-observational | 200 | not preregistered, not blinded | — |
| HUMAN-TRIAL | Tirzepatide to Reduce rEcurrence And Burden After Ablation of Atrial Fibrillation NCT07382024 · matched on "Tirzepatide" | human-rct | 200 | not blinded | — |
| HUMAN-TRIAL | A Clincial Study Testing Tirzepatide on Reproductive Function and Metabolic Health in Women With PCOS Who Are Overweight or Obese NCT07326111 · matched on "Tirzepatide" | human-rct | 198 | none stated | — |
| HUMAN-TRIAL | A Study of Eloralintide (LY3841136) and Eloralintide With Tirzepatide in Participants With Overweight or Obesity NCT06916065 · matched on "Tirzepatide" | human-observational | 188 | industry-funded, not blinded | — |
| HUMAN-TRIAL | Can Fat-Burning Shots Boost Fertility? Comparing Weight-Loss Injections vs. Healthy Habits for Obese Men With Low Sperm Health NCT07179120 · matched on "Tirzepatide" | human-rct | 180 | none stated | — |
| HUMAN-TRIAL | A First-In-Human Study of ARO-INHBE in Adults With Obesity With and Without Type 2 Diabetes Mellitus NCT06700538 · matched on "Tirzepatide" | human-rct | 180 | industry-funded | — |
| HUMAN-TRIAL | A Study of Tirzepatide (LY3298176) Once Weekly in Adolescent Participants Who Have Obesity or Overweight With Weight-Related Comorbidities NCT06075667 · matched on "LY-3298176" | human-rct | 160 | industry-funded | — |
| HUMAN-TRIAL | A Study to Evaluate ALN-2232 in Participants With Obesity NCT07463846 · matched on "Tirzepatide" | human-rct | 156 | industry-funded, not preregistered | — |
| HUMAN-TRIAL | A Study of Tirzepatide (LY3298176) in Participants With Overweight or Obesity and Chronic Kidney Disease With or Without Type 2 Diabetes NCT05536804 · matched on "Tirzepatide" | human-rct | 140 | industry-funded | — |
| HUMAN-TRIAL | A Study of LY3841136 in Japanese Participants With Obesity or Overweight NCT06297616 · matched on "Tirzepatide" | human-rct | 128 | industry-funded | — |
| HUMAN-TRIAL | Comparative Observation of Metabolic and Pharmacologic Adipose Remodeling With Enhanced Incretin AgonisTs NCT07589322 · matched on "Tirzepatide" | human-rct | 120 | not preregistered, not blinded | — |
| HUMAN-TRIAL | A Study of Tirzepatide in Overweight and Very Overweight Participants NCT04311411 · matched on "LY-3298176" | human-rct | 114 | industry-funded | — |
| HUMAN-TRIAL | A Phase 2 Study Evaluating the Co-Administration of Bremelanotide With Tirzepatide for the Treatment of Obesity NCT06565611 · matched on "Tirzepatide" | human-rct | 108 | industry-funded | — |
| HUMAN-TRIAL | Efficacy and Safety of Tirzepatide Versus Placebo or Lisdexamfetamine Dimesylate for Binge-Eating Disorder NCT06847399 · matched on "Tirzepatide" | human-rct | 105 | industry-funded | — |
| HUMAN-TRIAL | Phase 1/2a Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics and Effect on Body Weight of RN3161 as Monotherapy and in Combination With Tirzepatide in Adults With Overweight and Obesity NCT07245771 · matched on "Tirzepatide" | human-rct | 104 | industry-funded | — |
| HUMAN-TRIAL | Tolerance and Pharmacokinetic/Pharmacokinetic Study of IBI362 15mg in Patients With Moderate to Severe Obesity NCT07000955 · matched on "Tirzepatide" | human-rct | 98 | industry-funded | — |
| HUMAN-TRIAL | A Study of LY3841136 in Overweight and Obese Participants NCT06345066 · matched on "Tirzepatide" | human-rct | 96 | industry-funded | — |
| HUMAN-TRIAL | A Study of BGM0504 in Participants With Obesity NCT06911203 · matched on "Tirzepatide" | human-rct | 90 | industry-funded, not blinded | — |
| HUMAN-TRIAL | Tirzepatide Titration to Reduce Side Effects in Individuals With Obesity NCT07574723 · matched on "Tirzepatide" | human-rct | 68 | not blinded | — |
| HUMAN-TRIAL | Semaglutide and Tirzepatide for Genetic Aging Delay in Adults With Obesity NCT07293325 · matched on "Tirzepatide" | human-rct | 66 | not preregistered, not blinded | — |
| HUMAN-TRIAL | Effect of Tirzepatide and Bimagrumab on Body Composition, Insulin Sensitivity, and Bone in Adults With Obesity NCT05933499 · matched on "Tirzepatide" | human-rct | 63 | none stated | — |
| HUMAN-TRIAL | Comparison of Body Composition Changes With Weight Loss Interventions NCT07115069 · matched on "Tirzepatide" | human-observational | 60 | none stated | — |
| HUMAN-TRIAL | A Randomized, Double-blind, Placebo-controlled Study Evaluating the Effect of LAE102 Injection in Combination With Tirzepatide on Body in Obese Participants NCT07671391 · matched on "Tirzepatide" | human-rct | 60 | none stated | — |
| HUMAN-TRIAL | A Study to Measure Energy Expenditure and Food Intake in Participants With Obesity Using Tirzepatide NCT04081337 · matched on "LY-3298176" | human-rct | 55 | industry-funded | — |
| HUMAN-TRIAL | GLP-1R Actions on Muscle and the Skeleton NCT07154719 · matched on "Tirzepatide" | human-rct | 50 | not blinded | — |
| HUMAN-TRIAL | Effect of Semaglutide and Tirzepatide Combined With Exercise in Obesity NCT07319975 · matched on "Tirzepatide" | human-rct | 48 | none stated | — |
| HUMAN-TRIAL | Combination of Biologic and Anti-obesity Therapies in Psoriatic Arthritis NCT07443956 · matched on "Tirzepatide" | human-rct | 45 | industry-funded, not blinded | — |
| HUMAN-TRIAL | An Open-Label Tirzepatide Trial for Comorbid Obesity and Stimulant Use Disorder NCT07693608 · matched on "Tirzepatide" | not determined | 45 | not blinded | — |
| HUMAN-TRIAL | Tirzepatide for Alcohol Use Disorder NCT06994338 · matched on "Tirzepatide" | human-rct | 42 | none stated | — |
| HUMAN-TRIAL | A Study to Evaluate the Effect of Fasting Duration and Tirzepatide Withholding on the Amount of Food and Fluid in the Stomach in Participants With Type 2 Diabetes Mellitus and Participants With Overweight or Obesity Without Type 2 Diabetes Mellitus NCT07299084 · matched on "LY-3298176" | human-observational | 40 | industry-funded, not blinded | — |
| HUMAN-TRIAL | The Effect of Tirzepatide on Menopausal Vasomotor Symptoms and Biological Aging in Post-menopausal Women With Obesity NCT07218445 · matched on "Tirzepatide" | human-rct | 40 | none stated | — |
| HUMAN-TRIAL | A Study of LY3457263 in Obese Participants NCT05582096 · matched on "LY-3298176" | human-rct | 38 | industry-funded | — |
| HUMAN-TRIAL | A Study to Measure Stomach Emptying in Overweight Non-diabetic and Diabetic Participants Using Tirzepatide NCT04407234 · matched on "LY-3298176" | not determined | 36 | industry-funded, not blinded | — |
| HUMAN-TRIAL | Tirzepatide in PWS, HO and GNSO NCT06901245 · matched on "Tirzepatide" | human-observational | 36 | not blinded | — |
| HUMAN-TRIAL | Tirzepatide for Recurrent Weight Gain after Bariatric Procedures: Real-World Evidence of Efficacy and Safety. PMID 42247124 · DOI 10.1007/s11695-026-08754-7 · matched on "Tirzepatide" | human-observational | 34 | none stated | 2026-07-01 |
| HUMAN-TRIAL | Effect of Tirzepatide on Brown Adipose Tissue in Obesity NCT06893211 · matched on "Tirzepatide" | human-rct | 34 | none stated | — |
| HUMAN-TRIAL | Effects of Long-Acting GLP-1 (Glucagon-like Peptide-1) or Dual Incretin (GLP-1 and GIP [Glucose-dependent Insulinotropic Peptide]) Modulation on Gastric Motor Functions NCT06801015 · matched on "Tirzepatide" | human-rct | 30 | none stated | — |
| HUMAN-TRIAL | Tirzepatide's Role in Postmenopausal HR+ Breast Cancer Survivors NCT07257484 · matched on "Tirzepatide" | not determined | 30 | not blinded | — |
| HUMAN-TRIAL | Tirzepatide and Muscle Outcomes in Obesity NCT07373834 · matched on "Tirzepatide" | human-rct | 30 | none stated | — |
| HUMAN-TRIAL | Aging Well: Targeting Obesity With GLP-1 Agonists to Enhance Physical and Vascular Health in Postmenopausal Women NCT07057310 · matched on "Tirzepatide" | human-rct | 30 | not preregistered | — |
| HUMAN-TRIAL | A Study of Tirzepatide (LY3298176) in Pediatric Participants With Obesity NCT05696847 · matched on "LY-3298176" | human-rct | 28 | industry-funded | — |
| HUMAN-TRIAL | Role Of Metabolic Adaptation In Weight Regain NCT05766358 · matched on "Tirzepatide" | human-observational | 27 | not preregistered | — |
| HUMAN-TRIAL | Effects of Tirzepatide on Blood, Imaging and Breast Tissue Biomarkers NCT06485089 · matched on "Tirzepatide" | human-observational | 25 | none stated | — |
| HUMAN-TRIAL | Transcutaneous Auricular Vagus Nerve Stimulation for Poor Weight-Loss Response to Incretin Receptor Agonists NCT07619989 · matched on "Tirzepatide" | human-rct | 24 | not preregistered | — |
| HUMAN-TRIAL | The Effect of Exercise and Tirzepatide on Weight and Health Outcomes (EXER-MED) NCT07298915 · matched on "Tirzepatide" | human-rct | 24 | not blinded | — |
| HUMAN-TRIAL | Resistance Exercise and Incretin Mimetic for Cardiometabolic Health in Survivors of ALL With Obesity NCT07228741 · matched on "Tirzepatide" | not determined | 20 | not blinded | — |
| HUMAN-TRIAL | Tirzepatide in Obesity-Driven Endometrial Cancer NCT07065552 · matched on "Tirzepatide" | not determined | 20 | not blinded | — |
| HUMAN-TRIAL | Efficacy and Safety of Tirzepatide (Spartina) in Chronic Kidney Failure NCT07176663 · matched on "Tirzepatide" | not determined | 15 | not blinded | — |
| HUMAN-TRIAL | Effects of testosterone undecanoate as add-on therapy in obese hypogonadal men that are late responders to tirzepatide: a pilot study. PMID 41801155 · DOI 10.23736/s2724-6507.26.04541-0 · matched on "Tirzepatide" | human-observational | 10 | none stated | 2026-06-01 |
| HUMAN-TRIAL | Effects of Tirzepatide Plus Intensive Lifestyle Therapy on Body Weight and Metabolic Health in Latinos With Obesity NCT06009653 · matched on "Tirzepatide" | human-rct | 0 | industry-funded | — |
| HUMAN-TRIAL | A Study of Bimagrumab (LY3985863) and Tirzepatide (LY3298176), Alone or in Combination, in Participants With Obesity or Overweight With Type 2 Diabetes NCT06901349 · matched on "LY-3298176" | human-rct | 0 | industry-funded | — |
| HUMAN-TRIAL | Effect of Tirzepatide on Health-Related Quality of Life in Japanese Patients With Obesity Disease: Patient-Reported Outcomes From the SURMOUNT-J Study. PMID 42108080 · DOI 10.1111/dom.70850 · matched on "Tirzepatide" | human-rct | — | none stated | 2026-08-01 |
| HUMAN-TRIAL | Short-Term Combined Treatment With Tirzepatide and Metformin for Overweight/Obese Chinese Women With Polycystic Ovary Syndrome: A Prospective, Open-Label, Randomised Controlled Trial. PMID 42236268 · DOI 10.1111/dom.70966 · matched on "Tirzepatide" | human-rct | — | none stated | 2026-08-01 |
| HUMAN-TRIAL | Relationship of early rapid weight loss to efficacy and safety of tirzepatide and semaglutide for obesity: SURMOUNT-5 post hoc analysis. PMID 41865857 · DOI 10.1016/j.amjmed.2026.03.010 · matched on "Tirzepatide" | human-rct | — | none stated | 2026-07-01 |
| HUMAN-TRIAL | Apitegromab for lean mass preservation during tirzepatide-induced weight loss: a randomized, double-blind, placebo-controlled phase 2 trial. PMID 42260100 · DOI 10.1038/s41591-026-04440-4 · matched on "Tirzepatide" | human-rct | — | none stated | 2026-07-01 |
| HUMAN-TRIAL | Ixekizumab With or Without Tirzepatide in Adults With Psoriasis and Overweight or Obesity: A Phase 3b Randomized Clinical Trial. PMID 42139049 · DOI 10.1001/jamadermatol.2026.1753 · matched on "Tirzepatide" | human-rct | — | none stated | 2026-07-01 |
| HUMAN-TRIAL | Orforglipron for maintenance of body weight reduction: the double-blind, randomized phase 3b ATTAIN-MAINTAIN trial. PMID 42120723 · DOI 10.1038/s41591-026-04386-7 · matched on "Tirzepatide" | human-rct | — | none stated | 2026-07-01 |
| HUMAN-TRIAL | Six-Month Real-World Effectiveness, Persistence and Safety of Low-to-Moderate Dose Tirzepatide in Adults With Obesity: A Multicentre Observational Study. PMID 42037110 · DOI 10.1111/dom.70810 · matched on "Tirzepatide" | human-observational | — | none stated | 2026-07-01 |
| HUMAN-TRIAL | Tirzepatide for maintenance of bodyweight reduction in people with obesity in the USA (SURMOUNT-MAINTAIN): a multicentre, double-blind, randomised, placebo-controlled trial. PMID 42119587 · DOI 10.1016/s0140-6736(26)00656-2 · matched on "Tirzepatide" | human-rct | — | none stated | 2026-06-06 |
| HUMAN-TRIAL | Shifts in waist-to-height ratio categories within tirzepatide groups: a post-hoc analysis of SURMOUNT-1. PMID 42082865 · DOI 10.1007/s40618-026-02883-7 · matched on "Tirzepatide" | human-rct | — | none stated | 2026-06-01 |
| HUMAN-TRIAL | Preoperative GLP-1 Receptor Agonists and Thromboinflammatory Markers in Patients Undergoing Abdominoplasty: A Prospective Monocentric Study. PMID 41944875 · DOI 10.1007/s00266-026-05805-3 · matched on "Tirzepatide" | human-observational | — | none stated | 2026-06-01 |
| HUMAN-TRIAL | Short-term effect of tirzepatide on serum calcitonin in adults with obesity. PMID 42081121 · DOI 10.1007/s12020-026-04655-y · matched on "Tirzepatide" | human-observational | — | none stated | 2026-05-04 |
| HUMAN-TRIAL | Toward Precision Obesity Pharmacotherapy: Using the Eating Behavior Phenotype Scale (EFCA) in Real-World Clinical Practice. PMID 42124020 · DOI 10.3390/nu18091419 · matched on "Tirzepatide" | human-observational | — | none stated | 2026-04-30 |
| HUMAN-TRIAL | Real-world prescribing patterns and early weight and blood pressure outcomes of GLP-1-based therapies: a retrospective observational study in the United Arab Emirates. PMID 41968307 · DOI 10.1186/s12902-026-02273-3 · matched on "Tirzepatide" | human-observational | — | none stated | 2026-04-12 |
| HUMAN-TRIAL | A treat-to-target approach for obesity management: A post hoc analysis of the SURMOUNT-5 trial. PMID 41635114 · DOI 10.1111/dom.70531 · matched on "Tirzepatide" | human-observational | — | none stated | 2026-04-01 |
| HUMAN-TRIAL | Effectiveness and adherence in a tirzepatide-supported digital weight-loss programme in Australia: A real-world observational study. PMID 41532325 · DOI 10.1111/dom.70462 · matched on "Tirzepatide" | human-observational | — | none stated | 2026-04-01 |
| HUMAN-TRIAL | ARD-101, a gut-restricted TAS2R agonist, reduces hunger in adults and promotes weight loss in DIO mice with DPP-4 inhibition. PMID 41833222 · DOI 10.1016/j.molmet.2026.102340 · matched on "Tirzepatide" | human-rct | — | none stated | 2026-04-01 |
| HUMAN-TRIAL | Weight Changes With Tirzepatide and Concomitant Weight-Inducing Medications: Post Hoc Analysis of Randomized Clinical Trials. PMID 41885866 · DOI 10.1001/jamanetworkopen.2026.3274 · matched on "Tirzepatide" | human-rct | — | none stated | 2026-03-02 |
| HUMAN-TRIAL | Semaglutide and tirzepatide effects on cardiovascular outcomes in people with overweight or obesity in the real world (STEER). PMID 41491349 · DOI 10.1111/dom.70436 · matched on "Tirzepatide" | human-observational | — | none stated | 2026-03-01 |
| HUMAN-TRIAL | Efficacy and Safety of Tirzepatide in Japanese Participants With Obesity: A Subpopulation Analysis of the SURMOUNT-1 Trial. PMID 41612966 · DOI 10.1002/oby.70131 · matched on "Tirzepatide" | human-rct | — | none stated | 2026-03-01 |
| HUMAN-TRIAL | A real-world study of tirzepatide for weight loss in adults without diabetes mellitus. PMID 41354867 · DOI 10.1038/s41366-025-01986-0 · matched on "Tirzepatide" | human-observational | — | none stated | 2026-03-01 |
| HUMAN-TRIAL | Tirzepatide and change in uric acid and its association with weight reduction: post hoc analyses of the SURMOUNT-1 randomised placebo-controlled trial. PMID 41198460 · DOI 10.1016/j.ard.2025.10.009 · matched on "Tirzepatide" | human-rct | — | none stated | 2026-03-01 |
| HUMAN-TRIAL | Psychiatric Safety of Tirzepatide in People With Obesity and No Known Major Psychopathology: A Post Hoc Analysis of SURMOUNT. PMID 41537305 · DOI 10.1002/oby.70122 · matched on "Tirzepatide" | human-rct | — | none stated | 2026-03-01 |
| HUMAN-TRIAL | Cardiometabolic Parameter Change by Weight Regain on Tirzepatide Withdrawal in Adults With Obesity: A Post Hoc Analysis of the SURMOUNT-4 Trial. PMID 41284285 · DOI 10.1001/jamainternmed.2025.6112 · matched on "Tirzepatide" | human-rct | — | none stated | 2026-02-01 |
| HUMAN-TRIAL | Association of baseline characteristics with clinical outcomes of tirzepatide treatment in Japanese patients with obesity disease: A subgroup analysis of the SURMOUNT-J trial. PMID 41290555 · DOI 10.1111/dom.70315 · matched on "Tirzepatide" | human-rct | — | none stated | 2026-02-01 |
| HUMAN-TRIAL | Improved health-related quality of life with tirzepatide versus semaglutide in adults with obesity or overweight from the SURMOUNT-5 trial. PMID 41187971 · DOI 10.1111/dom.70215 · matched on "Tirzepatide" | human-rct | — | none stated | 2026-01-01 |
| HUMAN-TRIAL | Short-term effects of low-dose tirzepatide on lipid profile, glucose homeostasis and hepatic steatosis index in adults with obesity, but without diabetes mellitus: a prospective observational study. PMID 41075711 · DOI 10.1016/j.jdiacomp.2025.109181 · matched on "Tirzepatide" | human-observational | — | none stated | 2025-12-01 |
| HUMAN-TRIAL | In adults with obesity but without type 2 diabetes, tirzepatide increased weight loss at 72 wk compared with semaglutide. PMID 41183340 · DOI 10.7326/annals-25-04321-jc · matched on "Tirzepatide" | human-rct | — | none stated | 2025-11-01 |
| HUMAN-TRIAL | Impact of Body Mass Index, Central Adiposity, and Weight Loss on the Benefits of Tirzepatide in HFpEF: The SUMMIT Trial. PMID 40701669 · DOI 10.1016/j.jacc.2025.04.059 · matched on "LY3298176" | human-rct | — | none stated | 2025-07-29 |
| HUMAN-TRIAL | Tirzepatide Reduces LV Mass and Paracardiac Adipose Tissue in Obesity-Related Heart Failure: SUMMIT CMR Substudy. PMID 39566869 · DOI 10.1016/j.jacc.2024.11.001 · matched on "LY3298176" | human-rct | — | none stated | 2025-02-25 |
| ANIMAL | Efficacy of GLP-1 analog peptides, semaglutide, tirzepatide, and retatrutide on MC4R deficient obesity and their comparison. PMID 41723268 · DOI 10.1038/s41366-026-02025-2 · matched on "Tirzepatide" | animal | — | none stated | 2026-04-01 |
| ANIMAL | Tirzepatide reduces intracellular lipid content by promoting the browning of white fat via the cAMP signaling pathway. PMID 41506434 · DOI 10.1016/j.ejphar.2026.178523 · matched on "Tirzepatide" | animal | — | none stated | 2026-02-10 |
| ANIMAL | Differential effects of the anti-obesity drug tirzepatide on adipose tissues: Brown fat as a key target. PMID 41592522 · DOI 10.1016/j.biopha.2026.119057 · matched on "Tirzepatide" | animal | — | none stated | 2026-02-01 |
| ANIMAL | A metabolic comparison of GIPR agonism versus GIPR antagonism in male mice. PMID 41287212 · DOI 10.1111/dom.70300 · matched on "Tirzepatide" | animal | — | none stated | 2026-02-01 |
| ANIMAL | A melanocortin 4- and glucagon-like peptide 1 receptor multiple agonist for the treatment of diabetes and obesity. PMID 41093057 · DOI 10.1016/j.metabol.2025.156414 · matched on "Tirzepatide" | animal | — | none stated | 2026-01-01 |
| ANIMAL | Comparative analysis of LJ-4378 and tirzepatide in mouse models of obesity and weight regain. PMID 41199017 · DOI 10.1007/s12272-025-01575-9 · matched on "Tirzepatide" | animal | — | none stated | 2025-12-01 |
| ANIMAL | Tirzepatide improves extracellular matrix integrity and vascularization in pancreatic islets of a mouse model of obesity, diabetes, and menopause. PMID 41191986 · DOI 10.1016/j.bbrc.2025.152913 · matched on "Tirzepatide" | animal | — | none stated | 2025-11-19 |
| ANIMAL | GIPR agonism mediates weight-independent insulin sensitization by tirzepatide in obese mice. PMID 34003802 · DOI 10.1172/jci146353 · matched on "LY3298176" | animal | — | none stated | 2021-06-15 |
| PRECLINICAL | Comparative Efficacy of Metabolic/Bariatric Surgery Versus GLP-1 Receptor Agonists: A Network Meta-Analysis of Randomized Controlled Trials. PMID 41326176 · DOI 10.1002/oby.70100 · matched on "Tirzepatide" | not determined | 20015 | none stated | 2026-04-01 |
| PRECLINICAL | Weight Loss With GLP-1 Agonists in Nondiabetic Adults: Systematic Review and Network Meta-Analysis. PMID 41936548 · DOI 10.1002/oby.70169 · matched on "Tirzepatide" | not determined | 14059 | none stated | 2026-06-01 |
| PRECLINICAL | Effects of tirzepatide on weight management in patients with and without diabetes: a systematic review and meta-analysis. PMID 41015578 · DOI 10.1038/s41366-025-01920-4 · matched on "Tirzepatide" | not determined | 6641 | none stated | 2025-12-01 |
| PRECLINICAL | Enhancing economic modelling in obesity: integrating novel type 2 diabetes progression & obstructive sleep apnea remission - a UK case study. PMID 42021523 · DOI 10.1080/13696998.2026.2646079 · matched on "Tirzepatide" | not determined | — | none stated | 2026-12-01 |
| PRECLINICAL | Beyond weight loss: How metabolism in human adipocytes is shaped by GLP-1R agonists and dual GIPR/GLP-1R agonists. PMID 42229677 · DOI 10.1016/j.phrs.2026.108278 · matched on "Tirzepatide" | not determined | — | none stated | 2026-08-01 |
| PRECLINICAL | Weight Loss Medications in Youth: Decision-Making Experiences, Eating Behaviors, and Uncertainty About Endpoint. PMID 42233931 · DOI 10.1016/j.jadohealth.2026.03.017 · matched on "Tirzepatide" | not determined | — | none stated | 2026-08-01 |
| PRECLINICAL | Beyond weight loss: multisystem benefits of obesity medications. PMID 42208956 · DOI 10.1016/s2213-8587(26)00100-2 · matched on "Tirzepatide" | not determined | — | none stated | 2026-08-01 |
| PRECLINICAL | A trispecific GLP-1/anti-GIPR/FGF21 peptibody exhibits favorable metabolic effects in a diet-induced obesity model. PMID 42372355 · DOI 10.1016/j.biopha.2026.119717 · matched on "Tirzepatide" | not determined | — | none stated | 2026-08-01 |
| PRECLINICAL | Effect of short-term tirzepatide treatment on mean platelet volume in patients with obesity: a retrospective controlled study. PMID 42464179 · DOI 10.1186/s12902-026-02422-8 · matched on "Tirzepatide" | not determined | — | none stated | 2026-07-16 |
| PRECLINICAL | Comparative effects of drugs for adults with overweight or obesity: systematic review and network meta-analysis. PMID 42419792 · DOI 10.1136/bmj-2026-372161 · matched on "Tirzepatide" | not determined | — | none stated | 2026-07-08 |
| PRECLINICAL | Postshortage Compounded GLP-1 RA Market in 2 States With Potentially High Demand. PMID 42467450 · DOI 10.1001/jamahealthforum.2026.2207 · matched on "Tirzepatide" | not determined | — | none stated | 2026-07-02 |
| PRECLINICAL | Indirect Comparative Efficacy and Safety of Tirzepatide Versus Oral Semaglutide for the Treatment of Overweight and Obesity. PMID 42050884 · DOI 10.1111/dom.70773 · matched on "Tirzepatide" | not determined | — | none stated | 2026-07-01 |
| PRECLINICAL | Comparative Effectiveness of CagriSegma, Semaglutide, Cagrilintide and Tirzepatide in the Management of Overweight and Obesity: A Network Meta-Analysis of Randomized Clinical Trials. PMID 42207966 · DOI 10.1002/edm2.70248 · matched on "Tirzepatide" | not determined | — | none stated | 2026-07-01 |
| PRECLINICAL | American Society for Metabolic and Bariatric Surgery statement on the treatment options for patients with non-response and weight recurrence after metabolic and bariatric surgery. PMID 42150970 · DOI 10.1016/j.soard.2026.04.002 · matched on "Tirzepatide" | not determined | — | none stated | 2026-07-01 |
| PRECLINICAL | Effect of Incretin-Based and Nonpharmacologic Weight Loss on Body Composition : A Systematic Review. PMID 41996180 · DOI 10.7326/annals-25-00478 · matched on "Tirzepatide" | not determined | — | none stated | 2026-07-01 |
| PRECLINICAL | Comparative Efficacy and Safety of Tirzepatide in Asian and Non-Asian Adults With Obesity Without Diabetes: A Systematic Review and Meta-Analysis. PMID 42487213 · DOI 10.1002/edm2.70291 · matched on "Tirzepatide" | not determined | — | none stated | 2026-07-01 |
| PRECLINICAL | Approved weight loss drugs for obesity with a thorough emphasis on GLP-1 agonist medications: A systematic review. PMID 41991422 · DOI 10.1016/j.disamonth.2026.102113 · matched on "Tirzepatide" | not determined | — | none stated | 2026-07-01 |
| PRECLINICAL | Clinical Characteristics of Users of Weight Loss Drugs: Population-Based Case-Control Study. PMID 42086462 · DOI 10.1111/dom.70827 · matched on "Tirzepatide" | not determined | — | none stated | 2026-07-01 |
| PRECLINICAL | Incretin-Based Anti-obesity Medications in Polycystic Ovary Syndrome: The Evidence Map. PMID 42106472 · DOI 10.1007/s40265-026-02325-x · matched on "Tirzepatide" | not determined | — | none stated | 2026-07-01 |
| PRECLINICAL | Combination of prolonged water fasting and GLP-1 for refractory morbid obesity: Case report. PMID 41998348 · DOI 10.1038/s41430-026-01749-8 · matched on "Tirzepatide" | not determined | — | none stated | 2026-07-01 |
| PRECLINICAL | Cardiorenal outcomes of weight loss interventions in people with CKD and type 2 diabetes. PMID 41344888 · DOI 10.1093/ndt/gfaf258 · matched on "Tirzepatide" | not determined | — | none stated | 2026-06-30 |
| PRECLINICAL | [The role of obesity and weight reduction in obstructive sleep apnea]. PMID 42365594 · DOI 10.1556/650.2026.33589 · matched on "Tirzepatide" | not determined | — | none stated | 2026-06-28 |
| PRECLINICAL | Fat, muscle, and anti-obesity medications in cardiovascular disease prevention. PMID 41914150 · DOI 10.1093/eurheartj/ehag201 · matched on "Tirzepatide" | not determined | — | none stated | 2026-06-02 |
| PRECLINICAL | Disparities in Adolescent and Young Adult Obesity Medication Dispensing: A Retrospective Linked EHR-Pharmacy Cohort, 2020-2025. PMID 41612871 · DOI 10.1002/oby.70128 · matched on "Tirzepatide" | not determined | — | none stated | 2026-06-01 |
| PRECLINICAL | Data-driven prioritization of high-risk individuals for weight loss interventions. PMID 42062622 · DOI 10.1038/s41591-026-04353-2 · matched on "Tirzepatide" | not determined | — | none stated | 2026-06-01 |
| PRECLINICAL | Real-World Weight-Loss Outcomes in Weight-Reduced Patients Treated With Tirzepatide. PMID 41902614 · DOI 10.1002/oby.70179 · matched on "Tirzepatide" | not determined | — | none stated | 2026-06-01 |
| PRECLINICAL | Real-World Cardiovascular Outcomes of Obesity Treatment With Tirzepatide Versus Semaglutide in Non-Diabetic Adults. PMID 41891334 · DOI 10.1111/dom.70721 · matched on "Tirzepatide" | not determined | — | none stated | 2026-06-01 |
| PRECLINICAL | GLP-1 Receptor/Dual Agonists for Weight Loss: A Systematic Review and Network Meta-Analysis of RCTs. PMID 41872986 · DOI 10.1111/dom.70698 · matched on "Tirzepatide" | not determined | — | none stated | 2026-06-01 |
| PRECLINICAL | Obesity Treatments and Weight Changes in Clinical Practice After Discontinuation of Semaglutide or Tirzepatide. PMID 41816857 · DOI 10.1111/dom.70660 · matched on "Tirzepatide" | not determined | — | none stated | 2026-06-01 |
| PRECLINICAL | ICER report demonstrates both the value and challenges in financing of weight loss medications. PMID 42166309 · DOI 10.18553/jmcp.2026.32.6.753 · matched on "Tirzepatide" | not determined | — | none stated | 2026-06-01 |
| PRECLINICAL | Body image in the age of GLP-1s: Emerging questions for research and practice. PMID 42030632 · DOI 10.1016/j.bodyim.2026.102095 · matched on "Tirzepatide" | not determined | — | none stated | 2026-06-01 |
| PRECLINICAL | Lean Mass Changes With Incretin Therapy Versus Lifestyle Intervention: A Systematic Review and Meta-Analysis of Randomised Controlled Trials. PMID 41877354 · DOI 10.1111/dom.70666 · matched on "Tirzepatide" | not determined | — | none stated | 2026-06-01 |
| PRECLINICAL | Tirzepatide and Reduced Risk of Diabetic Retinopathy and Related Complications: A Multicenter US Cohort Study. PMID 41577258 · DOI 10.1016/j.ophtha.2026.01.013 · matched on "Tirzepatide" | not determined | — | none stated | 2026-06-01 |
| PRECLINICAL | Beyond weight loss: tirzepatide as a dual GIP/GLP-1 receptor agonist for obstructive sleep apnea. PMID 41405280 · DOI 10.1097/med.0000000000000949 · matched on "Tirzepatide" | not determined | — | none stated | 2026-06-01 |
| PRECLINICAL | Glucagon-Like Peptide-1 Receptor Agonists as Adjunctive Therapy for Hidradenitis Suppurativa in Patients With Overweight/Obesity: A Narrative Review of Efficacy, Safety, and Quality-of-Life Outcomes. PMID 41729201 · DOI 10.1111/ijd.70346 · matched on "Tirzepatide" | not determined | — | none stated | 2026-06-01 |
| PRECLINICAL | Childhood obesity and cardiac risk in youth: Emerging challenges toward 2050. PMID 41933725 · DOI 10.1016/j.clnesp.2026.103260 · matched on "Tirzepatide" | not determined | — | none stated | 2026-06-01 |
| PRECLINICAL | Health-Related Quality of Life and Work-Related Outcomes in People with Obesity or Overweight Treated with Tirzepatide or Other Obesity Medications: United States Results from the Adelphi Real World Obesity Disease Specific Programme. PMID 41965443 · DOI 10.1007/s12325-026-03580-w · matched on "Tirzepatide" | not determined | — | none stated | 2026-06-01 |
| PRECLINICAL | Comparative pharmacovigilance analysis of suicidality-related adverse events among GLP-1 and non-GLP-1 anti-obesity drugs in the FDA Adverse Event Reporting System. PMID 41739406 · DOI 10.1007/s11096-026-02099-y · matched on "Tirzepatide" | not determined | — | none stated | 2026-06-01 |
| PRECLINICAL | Medical nutrition in the glucagon-like peptide-1 (GLP-1) era: Protein strategies, micronutrient monitoring, and lean mass preservation. PMID 42036071 · DOI 10.1016/j.clnesp.2026.103305 · matched on "Tirzepatide" | not determined | — | none stated | 2026-06-01 |
| PRECLINICAL | Effectiveness of Telemedicine Prescribing and a Long-Acting Obesity Medication Behavioral Program: A 24-Week Single-Arm Study. PMID 41253738 · DOI 10.1002/oby.70056 · matched on "Tirzepatide" | not determined | — | none stated | 2026-06-01 |
| PRECLINICAL | Impact of Tirzepatide Therapy on Thyroid Disease: Understanding Risks and Emerging Insights. PMID 42145153 · DOI 10.1111/cob.70084 · matched on "Tirzepatide" | not determined | — | none stated | 2026-06-01 |
| PRECLINICAL | Nutrition Strategies for Next-Generation Incretin Therapies: A Systematic Scoping Review of the Current Evidence. PMID 41500509 · DOI 10.1111/obr.70079 · matched on "Tirzepatide" | not determined | — | none stated | 2026-06-01 |
| PRECLINICAL | Reduced-Frequency GLP1 Therapy Maintains Weight, Body Composition, and Metabolic Syndrome Improvements: A Case Series. PMID 41732031 · DOI 10.1002/oby.70137 · matched on "Tirzepatide" | not determined | — | none stated | 2026-06-01 |
| PRECLINICAL | Nutrition-First Support for GLP-1 and Dual Incretin Therapy in Obesity: A Practical Framework for Dietary Management, Symptom Tolerability, and Long-Term Weight Maintenance. PMID 42280393 · DOI 10.3390/nu18111751 · matched on "Tirzepatide" | not determined | — | none stated | 2026-05-29 |
| PRECLINICAL | After the Prescription: The Clinical Support Gap in Telehealth-Based GLP-1 Care. PMID 42206886 · DOI 10.2196/101874 · matched on "Tirzepatide" | not determined | — | none stated | 2026-05-28 |
| PRECLINICAL | To Reenvision and Redefine: Considering the Role of Lifestyle Interventions in the New Era of Second-Generation Obesity Management Medications. PMID 42183911 · DOI 10.1007/s11883-026-01426-y · matched on "Tirzepatide" | not determined | — | none stated | 2026-05-25 |
| PRECLINICAL | Benefits of Incretin Therapy on Ovarian Function: A Scientific Literature Review. PMID 42278283 · DOI 10.3390/ijms27114752 · matched on "Tirzepatide" | not determined | — | none stated | 2026-05-25 |
| PRECLINICAL | GLP-1 Receptor Agonists and Dual GIP/GLP-1 Receptor Agonists in Children and Adolescents with Obesity: Clinical Outcomes and the Impact of Nutritional and Behavioral Co-Interventions-A Systematic Review. PMID 42280306 · DOI 10.3390/nu18111662 · matched on "Tirzepatide" | not determined | — | none stated | 2026-05-22 |
| PRECLINICAL | Swiss obesity clinical practice guidance. PMID 42312974 · DOI 10.57187/5415 · matched on "Tirzepatide" | not determined | — | none stated | 2026-05-19 |
| PRECLINICAL | Cutaneous Allodynia Associated With GLP-1RA Tirzepatide for Weight Management: A Case Series. PMID 42101979 · DOI 10.12659/ajcr.952158 · matched on "Tirzepatide" | not determined | — | none stated | 2026-05-08 |
| PRECLINICAL | Mental health outcomes in obesity interventions with GLP-1 receptor agonists: is it similar to other obesity interventions? A narrative review with systematic evidence synthesis. PMID 41491273 · DOI 10.1038/s41366-025-02002-1 · matched on "Tirzepatide" | not determined | — | none stated | 2026-05-01 |
| PRECLINICAL | Brachial Plexopathy Following Rapid Weight Loss from Tirzepatide: A Case Report. PMID 42263282 · matched on "Tirzepatide" | not determined | — | none stated | 2026-05-01 |
| PRECLINICAL | Weight loss as the optimal cardiometabolic management strategy for preventing and treating heart failure. PMID 41802118 · DOI 10.1097/hco.0000000000001284 · matched on "Tirzepatide" | not determined | — | none stated | 2026-05-01 |
| PRECLINICAL | Pre-Treatment Concerns and Their Association With Functioning and Well-Being During Incretin-Based Therapy: A Cross-Sectional Study. PMID 41733056 · DOI 10.1111/dom.70599 · matched on "Tirzepatide" | not determined | — | none stated | 2026-05-01 |
| PRECLINICAL | Weight Loss as a Determinant of Histological Improvement in Metabolic Dysfunction-Associated Steatotic Liver Disease in People With Obesity. A Systematic Review and Network Meta-Analysis of Randomised Clinical Trials. PMID 41804193 · DOI 10.1111/dom.70617 · matched on "Tirzepatide" | not determined | — | none stated | 2026-05-01 |
| PRECLINICAL | Comparison of Clinical Efficacy and Safety of Tirzepatide, Liraglutide and Semaglutide in Patients with Obesity and Without T2D: A Bayesian Network Meta-Analysis of Randomised Controlled Trials. PMID 41820778 · DOI 10.1007/s12325-026-03523-5 · matched on "Tirzepatide" | not determined | — | none stated | 2026-05-01 |
| PRECLINICAL | Comparison of pharmacotherapies for obesity with sleeve gastrectomy: a network meta-analysis and systematic review. PMID 41968780 · DOI 10.1080/17446651.2026.2656247 · matched on "Tirzepatide" | not determined | — | none stated | 2026-05-01 |
| PRECLINICAL | A novel, widespread impurity in mass-compounded tirzepatide/B12 products: potential patient safety implications. PMID 42010938 · DOI 10.1080/14740338.2026.2663185 · matched on "Tirzepatide" | not determined | — | none stated | 2026-05-01 |
| PRECLINICAL | Real-Life Data of Tirzepatide Use to Support Lifestyle Modification in Patients with Metabolic Syndrome. PMID 42075085 · DOI 10.3390/nu18081275 · matched on "Tirzepatide" | not determined | — | none stated | 2026-04-17 |
| PRECLINICAL | Pharmacologic Treatment of Obesity in the Context of Type 2 Diabetes. PMID 41973192 · DOI 10.1007/s11892-026-01626-5 · matched on "Tirzepatide" | not determined | — | none stated | 2026-04-13 |
| PRECLINICAL | Tirzepatide on physical function in adults with overweight or obesity: A systematic review and meta-analysis. PMID 41705736 · DOI 10.1111/dom.70529 · matched on "Tirzepatide" | not determined | — | none stated | 2026-04-01 |
| PRECLINICAL | Appetite, Obesity, Metabolism, and Malignancy: Do Incretin-Mimetic Drugs Reduce Cancer Risk? PMID 41918364 · DOI 10.1158/1940-6207.capr-26-0018 · matched on "Tirzepatide" | not determined | — | none stated | 2026-04-01 |
| PRECLINICAL | Obesity Management: Pharmacotherapy. PMID 42101582 · matched on "Tirzepatide" | not determined | — | none stated | 2026-04-01 |
| PRECLINICAL | The Necessity of POMC and MC3R Analysis in the First-Level Diagnosis of Monogenic Obesity: The Experience of Two Italian Centers. PMID 42074523 · DOI 10.3390/genes17040405 · matched on "Tirzepatide" | not determined | — | none stated | 2026-03-31 |
| PRECLINICAL | GLP-1 receptor agonists for weight loss: A systematic review and meta-analysis of randomized controlled trials. PMID 41824845 · DOI 10.1097/md.0000000000047994 · matched on "Tirzepatide" | not determined | — | none stated | 2026-03-13 |
| PRECLINICAL | Resistant and Refractory Obesity: The Complexity of Anti-Obesity Therapy Failure. PMID 41898403 · DOI 10.3390/ijms27062539 · matched on "Tirzepatide" | not determined | — | none stated | 2026-03-10 |
| PRECLINICAL | Prospective Comparative Analysis of Synchronous Abdominoplasty and Mastopexy in Bariatric and Nonbariatric Massive Weight Loss Patients: Highlighting the Rising Trend of GLP-1 Analog Use. PMID 41687026 · DOI 10.1097/sap.0000000000004673 · matched on "Tirzepatide" | not determined | — | none stated | 2026-03-01 |
| PRECLINICAL | Head-to-head comparison of tirzepatide and semaglutide for weight loss: A systematic review and meta-analysis. PMID 41723034 · DOI 10.1016/j.orcp.2026.02.002 · matched on "Tirzepatide" | not determined | — | none stated | 2026-03-01 |
| PRECLINICAL | Bariatric Surgery in the Era of GLP1RA: A Narrative Review. PMID 41627368 · DOI 10.1007/s12325-026-03494-7 · matched on "Tirzepatide" | not determined | — | none stated | 2026-03-01 |