| PRECLINICAL | evidence | Oral semaglutide (Rybelsus) for type 2 diabetes. | Ozempic | Glycemic control | 2019-10-21 |
| PRECLINICAL | evidence | [Semaglutide, once weekly GLP-1 receptor agonist (Ozempic(R))]. | Ozempic | Glycemic control | 2019-09-01 |
| PRECLINICAL | evidence | Semaglutide (Ozempic) for Type 2 Diabetes Mellitus. | Ozempic | Glycemic control | 2019-07-15 |
| PRECLINICAL | evidence | | Ozempic | — | 2019-06-01 |
| PRECLINICAL | evidence | Cardiovascular benefits of SGLT2 inhibitors and GLP-1 receptor agonists in Type 2 diabetes. | Ozempic | Glycemic control | 2019-02-25 |
| PRECLINICAL | evidence | Subcutaneous semaglutide (NN9535) for the treatment of type 2 diabetes. | NN9535 | Glycemic control | 2018-03-01 |
| PRECLINICAL | evidence | Semaglutide: First Global Approval. | Ozempic | Glycemic control | 2018-02-01 |
| PRECLINICAL | evidence | Semaglutide (Ozempic)--another injectable GLP-1 receptor agonist for type 2 diabetes. | Ozempic | Glycemic control | 2018-01-29 |
| PRECLINICAL | evidence | BPI-3016, a novel long-acting hGLP-1 analogue for the treatment of Type 2 diabetes mellitus. | NN9535 | Glycemic control | 2017-08-01 |
| PRECLINICAL | evidence | Glucagon-Like Peptide-1 (GLP-1) Analogues. | Ozempic | — | 2012-01-01 |
| PRECLINICAL | evidence | Semaglutide. | Ozempic | — | 2006-01-01 |
| PRECLINICAL | evidence | Semaglutida. | semaglutida | — | 1994-01-01 |
| INDEPENDENT-REVIEW | review | Thanks for posting to r/semaglutide!
A brief reminder about our rules. We do not permit the discussion of non-FDA approved formulations of semaglutide, nor do we permit selling or offering for sale any medication, including by private message. Do not request or respond to a private message from anyone offering such, they are not endorsed by this sub.
If you’re just starting out, you may want to | COMMUNITY | — | 2026-07-27 |
| INDEPENDENT-REVIEW | review | U look great … I love the Semaglutide I lost 37 pounds literally in 7/8 weeks . | COMMUNITY | — | 2026-07-27 |
| INDEPENDENT-REVIEW | review | I think my comment got autoremoved because of the link, but the important bit was:
> basically jump 0.5 mg every four weeks, so go for 1.0 mg next.
If you google "semaglutide dosage chart" you'll find some examples. | COMMUNITY | — | 2026-07-27 |
| INDEPENDENT-REVIEW | review | Congratulations!! Your results are such an inspiration! I am starting at a very similar weight and finals goal is 130lbs. Have you been on Semaglutide the entire time? Do you know how long you stayed on each dosage? | COMMUNITY | — | 2026-07-27 |
| INDEPENDENT-REVIEW | review | Things I Wish I Knew Before Starting Semaglutide
Before starting semaglutide, I spent a lot of time reading through posts in this community, and they helped me know what to expect. A few things that made the biggest difference were staying hydrated, making protein a priority, eating smaller meals when my appetite changed, and being patient with the process. I also learned that weight loss isn't | COMMUNITY | — | 2026-07-27 |
| INDEPENDENT-REVIEW | review | Ozempic and Wegovy are different brand names for the same active drug, semaglutide | COMMUNITY | — | 2026-07-27 |
| INDEPENDENT-REVIEW | review | This happened to me as well after taking semaglutide | COMMUNITY | — | 2026-07-27 |
| INDEPENDENT-REVIEW | review | Semaglutide and Creatine? | COMMUNITY | — | 2026-07-27 |
| INDEPENDENT-REVIEW | review | I had been tortured by hot flashes for years. Started taking Semaglutide and they almost immediately stopped. I haven’t had one hot flash since. | COMMUNITY | — | 2026-07-27 |
| INDEPENDENT-REVIEW | review | I’m the opposite. I love food, I really enjoy eating, and I hate not being able to enjoy it on Semaglutide. I really need to get back on it to lose weight, but I am not motivated. | COMMUNITY | — | 2026-07-27 |
| INDEPENDENT-REVIEW | review | Thanks for posting to r/semaglutide!
A brief reminder about our rules. We do not permit the discussion of non-FDA approved formulations of semaglutide, nor do we permit selling or offering for sale any medication, including by private message. Do not request or respond to a private message from anyone offering such, they are not endorsed by this sub.
If you’re just starting out, you may want to | COMMUNITY | — | 2026-07-26 |
| INDEPENDENT-REVIEW | review | I stopped semaglutide for 1 full year and, while I started gaining weight again, the interest in alcohol didn't come back...
(Went on semaglutide again because of the weight gain though) | COMMUNITY | — | 2026-07-26 |
| INDEPENDENT-REVIEW | review | Hi!! I am Located in Orlando could you please share some more information? 🙏🏻🙏🏻 do they sell it without prescription in that pharmacy? Whats the dose? I am currently paying 380 without insurance for semaglutide 1.7 through my primary care physician | COMMUNITY | — | 2026-07-26 |
| INDEPENDENT-REVIEW | review | I spent my entire adult life suffering with hunger and yo yo dieting. I feel like semaglutide has corrected an “imbalance” that has been life changing. I don’t plan on ever stopping a GLP (open to changing as medical innovations happen). | COMMUNITY | — | 2026-07-26 |
| INDEPENDENT-REVIEW | review | Do you drink coffee? For me, it feels like caffeine stays in my system longer. I guess semaglutide should not affect how fast the caffeine breaks down, but maybe it affects how long it takes for the caffeine to enter the system.
My sleeping problems seemed to end after I stopped drinking coffee after lunch. However, idk if this was the actual cause or not. | COMMUNITY | — | 2026-07-26 |
| INDEPENDENT-REVIEW | review | Does anyone else prefer life on Semaglutide, regardless of the weight loss?
I really enjoy not having intrusive food thoughts, constantly needing to debate with myself what/when to eat. I never spend time feeling disgusted with myself for over eating. It reminds me of my late 30’s, when I stopped constantly thinking of women, it was liberating, freeing up my mind. And best of all, I NEVER | COMMUNITY | — | 2026-07-26 |
| INDEPENDENT-REVIEW | review | New to researching semaglutide. I'm nervous it will mess with my current anxiety medication. Any advice out there? 40+ | COMMUNITY | — | 2026-07-26 |
| INDEPENDENT-REVIEW | review | Semaglutide (B12 & Glycerin)
SW: 205
GW: 165
CW: 195
1 Month (5 weeks) now at 10 units
10lbs lost right at 1mg (10 units). | COMMUNITY | — | 2026-07-26 |
| INDEPENDENT-REVIEW | review | I am having the exact same issues. I’ve been on the injections for four weeks now. I started with sublingual semaglutide three months ago and noticed a slight uptick in anxiety. Since switching to injections recently, the anxiety is paralyzing. I’m going to discontinue use of it. | COMMUNITY | — | 2026-07-26 |
| INDEPENDENT-REVIEW | review | Starting weight 218 lbs in February 2024, current weight 118 lbs; I hit that and have maintained since July 2025. I’m 5’4. Started on semaglutide and lost the first 85lbs then switched to tirzepatide due to anhedonia in March 2025 and lost the last 15 lbs and regained my interest in fun. I will happily be on this med for life. | COMMUNITY | — | 2026-07-26 |
| INDEPENDENT-REVIEW | review | Thanks for posting to r/semaglutide!
A brief reminder about our rules. We do not permit the discussion of non-FDA approved formulations of semaglutide, nor do we permit selling or offering for sale any medication, including by private message. Do not request or respond to a private message from anyone offering such, they are not endorsed by this sub.
If you’re just starting out, you may want to | COMMUNITY | — | 2026-07-25 |
| INDEPENDENT-REVIEW | review | Anyone using the higher dose of Semaglutide of 7.2mg?
Since the FDA has approved the 7.2mg dose of Wegovy, has anyone titrated up their dose from 2.4mg? I upped mine from 2.4mg to 5mg and have had great results again. | COMMUNITY | — | 2026-07-25 |
| INDEPENDENT-REVIEW | review | Anyone using the higher dose of Semaglutide of 7.2mg?
[removed] | COMMUNITY | — | 2026-07-25 |
| INDEPENDENT-REVIEW | review | If you are in the USA, the self pay pricing for brand name Wegovy is consistent across the board. There are no extra discounts at this time. Here are the prices:
https://www.novocare.com/content/dam/novonordisk/novocare/redesign/pdf/Wegovy_Price_Guide.pdf
The way one can save money is by having their PCP prescribe the medication so they can avid paying a monthly membership fee just to get a | COMMUNITY | — | 2026-07-25 |
| INDEPENDENT-REVIEW | review | I’ve been ultra low carb since having kids but slowly year after year I just gain more weight. I feel well on low carb. No crashes. Steady energy. Sleep well. BUTTTT I finally succumbed to trying semaglutide and that came with a dietitian. She swears by eating a decent amount of carbs because they are lower calories than fat and protein (my primary food intake). I’m reluctantly trying it. We will | COMMUNITY | — | 2026-07-25 |
| INDEPENDENT-REVIEW | review | Ah love to hear this! There aren’t too many discussions on experiences with apo-semaglutide yet so this is great to know. | COMMUNITY | — | 2026-07-25 |
| INDEPENDENT-REVIEW | review | I’m on my first 0.25mg dose of apo-semaglutide, about to jab the second tomorrow. Food noise and appetite control was fairly immediate. I am eating less, but maybe not as extreme as others have mentioned. I’d say portions are 2/3 of what I used to eat. There are days where I feel like I came out a buffet, and days where I am not full and can potentially eat more (I stop myself for these | COMMUNITY | — | 2026-07-25 |
| INDEPENDENT-REVIEW | review | How much can you eat on Semaglutide (vs. Before)?
Going to be starting on Apo-Semaglutide soon (🇨🇦 generic) and have been really excited/hopeful for the food noise suppressing part of it. But, I’ve also read many times on here where people who are planning to start soon talk about what they’ll be eating/their healthy meal plans and many comment saying they won’t be able to eat that much.
For | COMMUNITY | — | 2026-07-25 |
| INDEPENDENT-REVIEW | review | For me, semaglutide is a crutch, not a wonder drug. I suffer from insane food nice normally. And sena turns it off. It makes me a tiny bit less hungry.
But u still count calories, track protein, and go to the gym. And it's that stuff that causes the weight loss. I know cause if I stop, so does the weight loss!
Sema has saved me from a life time food burden and I hope i never gave to get off | COMMUNITY | — | 2026-07-25 |
| INDEPENDENT-REVIEW | review | You need to use some common sense about this.
Semaglutide slows down digestion. So if you have unhealthy food and it sits on your gut longer, it comes out as suffer burps. Eat healthy food fill your plate 1/2 vegetables 1/4 starchor grains 1/4 protein. If you get Chinese food order broccoli chicken not something fried in batter. Same at McDonald's order grilled chicken lite mayo. You need | COMMUNITY | — | 2026-07-25 |
| INDEPENDENT-REVIEW | review | i find that the people who think it's "too good to be true" are the ones who seem to think this is a magic serum that just melts weight off. it's not.
for context, i lost a good chunk of weight many years ago using weight watchers. i had to track every single thing i ate and drank, and stay within daily parameters. yes, it worked, because i worked the program.
**it's the EXACT SAME with | COMMUNITY | — | 2026-07-25 |
| INDEPENDENT-REVIEW | review | Update: five months off semaglutide
First picture was pre sema. Second is at my lowest weight. Third is one month after stopping sema. Last pic is now!
I was on (name brand) semaglutide from May 2025 until February of this year. I started at 180lb. I lost 43lb, putting me at 137lb in the second picture. Then I stagnated for a while. After I stopped sema, I quickly gained back about 13lb. | COMMUNITY | — | 2026-07-25 |
| INDEPENDENT-REVIEW | review | Semaglutide vs Tirzepatide?
Hi I’m debating which one to go on. I was prescribed mounjaro (tirzepatide) by my physician but I don’t have insurance to cover it. I live in Canada and it would cost me over 300$. Whereas I can ask to be predicted Generic Ozempic (Semaglutide) which would be just over 100$/ month.
I’m in a pickle. Can I hear your experiences on either one! I’m 26, 5’1 156 pounds and | COMMUNITY | — | 2026-07-25 |
| INDEPENDENT-REVIEW | review | Is click counting the same for Apo semaglutide and Ozempic?
Hi everyone,
I live in Canada and have been prescribed the generic Ozempic (1mg) pen. My doctor told me to do click counting, which I did on my original Ozempic pen as well. I was told to do the same 36 clicks. Is that what others are doing, and how are they finding the generic?
Thank ya! | COMMUNITY | — | 2026-07-25 |
| INDEPENDENT-REVIEW | review | Yes, they are both glp-1 medications, they both supress your appetite. Tirzepatide is a little more expensive, so I would recommend starting off with semaglutide , some people do great on it. If sema doesn’t work for you, you can always switch to Tirzepatide. | COMMUNITY | — | 2026-07-25 |
| INDEPENDENT-REVIEW | review | Thanks for posting to r/semaglutide!
A brief reminder about our rules. We do not permit the discussion of non-FDA approved formulations of semaglutide, nor do we permit selling or offering for sale any medication, including by private message. Do not request or respond to a private message from anyone offering such, they are not endorsed by this sub.
If you’re just starting out, you may want to | COMMUNITY | — | 2026-07-24 |
| INDEPENDENT-REVIEW | review | Why do so many people regain weight after stopping GLP 1 meds (Wegovy / Zepbound / Saxenda / Foundayo / tirzepatide / semaglutide)?
A stat that surprised me: In the STEP‑1 extension study, people who stopped GLP‑1 meds (*Wegovy / Zepbound / Saxenda / Foundayo / tirzepatide / semaglutide)* regained **about two‑thirds of the weight they lost** within a year. Not everyone regains that much — but the | COMMUNITY | — | 2026-07-23 |
| INDEPENDENT-REVIEW | review | semaglutide to tirzepatide | COMMUNITY | — | 2026-07-22 |