| HUMAN-TRIAL | evidence | Intradermal injections of a hair growth factor formulation for enhancement of human hair regrowth - safety and efficacy evaluation in a first-in-man pilot clinical study. | Copper tripeptide-1 | Skin appearance & aging · human-observational · n = 1000 | 2018-10-01 |
| HUMAN-TRIAL | evidence | Effects of topical copper tripeptide complex on CO2 laser-resurfaced skin. | GHK | Skin appearance & aging · human-rct · n = 13 | 2006-07-01 |
| HUMAN-TRIAL | evidence | Effects of topical copper tripeptide complex on CO2 laser-resurfaced skin. | Copper tripeptide | human-rct | 2006-07-01 |
| HUMAN-TRIAL | evidence | Topical GHK-Cu Gel for Acute Skin Wound Healing | GHK | human-rct · n = 60 | — |
| REGULATORY | regulatory | D-0051-2026 — GHK-Cu (Copper Peptide) for Injection, all strengths and presentations, GenoGenix, LLC, 2840 NW 2nd Ave Ste 204 Boca Raton, FL 33431-6692. | FDA | — | 2025-07-30 |
| REGULATORY | regulatory | YVTYVT Copper Peptides Face Serum — FDA prescribing information | FDA | — | 2025-03-16 |
| REGULATORY | regulatory | YVTYVT COPPER PEPTIDES FACIAL SERUM — FDA prescribing information | FDA | — | 2025-02-28 |
| REGULATORY | regulatory | D-0141-2021 — GHK-CU, 10 MG/ML, 5 ML vial, The Guyer Institute of Molecular Medicine, Indianapolis, IN | FDA | — | 2020-11-30 |
| ANIMAL | evidence | Glycyl-L-histidyl-L-lysine-Cu2(+) (GHK-Cu) Attenuates CuSO(4) or LPS induced-inflammation in Zebrafish larvae model. | GHK | Inflammation · animal | 2026-05-10 |
| ANIMAL | evidence | Glycyl-L-histidyl-L-lysine-Cu2(+) (GHK-Cu) Attenuates CuSO(4) or LPS induced-inflammation in Zebrafish larvae model. | GHK-Cu | animal | 2026-05-10 |
| ANIMAL | evidence | The GHK-Cu delays aging in Caenorhabditis elegans via coordinated regulation of mitochondrial function and activation of DAF-16/SKN-1 pathways. | GHK | Longevity & cellular aging · animal | 2026-05-05 |
| ANIMAL | evidence | The GHK-Cu delays aging in Caenorhabditis elegans via coordinated regulation of mitochondrial function and activation of DAF-16/SKN-1 pathways. | Cu-GHK | animal | 2026-05-05 |
| ANIMAL | evidence | Elastic cationic liposomal nanogels: a novel platform for topical nicotinamide mononucleotide delivery. | GHK | animal | 2026-03-01 |
| ANIMAL | evidence | An injectable hydroxyapatite microsphere filler loaded with GHK-Cu tripeptide for anti-Inflammatory and antioxidant. | glycyl-L-histidyl-L-lysine copper | animal | 2025-12-01 |
| ANIMAL | evidence | An injectable hydroxyapatite microsphere filler loaded with GHK-Cu tripeptide for anti-Inflammatory and antioxidant. | GHK | Inflammation · animal | 2025-12-01 |
| ANIMAL | evidence | Anxiolytic Effect of GHK-PGP Peptide and Its Structural Analogues in a Test with Punished Behavior. | GHK | animal | 2025-09-01 |
| ANIMAL | evidence | Genetically Programmed Single-Component Protein Hydrogel for Spinal Cord Injury Repair. | GHK | animal | 2025-03-01 |
| ANIMAL | evidence | Effects of combined postweaning social isolation and ketamine administration on schizophrenia-like behaviour in male Sprague Dawley rats. | GHK | animal | 2025-01-05 |
| ANIMAL | evidence | Hemostatic Effect and Mechanism of Epidermal Growth Factor-Hemostatic Powder after Endoscopic Submucosal Dissection in a Porcine Model. | GHK | animal | 2023-07-15 |
| ANIMAL | evidence | Biomimetic Hydrogel Scaffolds with Copper Peptide-Functionalized RADA16 Nanofiber Improve Wound Healing in Diabetes. | GHK | animal | 2022-08-01 |
| ANIMAL | evidence | Glutathione Protects the Developing Heart from Defects and Global DNA Hypomethylation Induced by Prenatal Alcohol Exposure. | GHK | animal | 2021-01-01 |
| ANIMAL | evidence | Expression and Purification of Recombinant GHK Tripeptides Are Able to Protect against Acute Cardiotoxicity from Exposure to Waterborne-Copper in Zebrafish. | GHK | animal | 2020-08-19 |
| ANIMAL | evidence | Expression and Purification of Recombinant GHK Tripeptides Are Able to Protect against Acute Cardiotoxicity from Exposure to Waterborne-Copper in Zebrafish. | GHK-Cu | animal | 2020-08-19 |
| ANIMAL | evidence | Protective effects of GHK-Cu in bleomycin-induced pulmonary fibrosis via anti-oxidative stress and anti-inflammation pathways. | GHK-Cu | animal | 2020-01-15 |
| ANIMAL | evidence | Protective effects of GHK-Cu in bleomycin-induced pulmonary fibrosis via anti-oxidative stress and anti-inflammation pathways. | GHK | Inflammation · animal | 2020-01-15 |
| ANIMAL | evidence | Potent Sodium/Glucose Cotransporter SGLT1/2 Dual Inhibition Improves Glycemic Control Without Marked Gastrointestinal Adaptation or Colonic Microbiota Changes in Rodents. | GHK | animal | 2018-06-01 |
| ANIMAL | evidence | The tri-peptide GHK-Cu complex ameliorates lipopolysaccharide-induced acute lung injury in mice. | GHK-Cu | animal | 2016-09-06 |
| ANIMAL | evidence | The tri-peptide GHK-Cu complex ameliorates lipopolysaccharide-induced acute lung injury in mice. | GHK | animal | 2016-09-06 |
| ANIMAL | evidence | Tripeptide-copper complex GHK-Cu (II) transiently improved healing outcome in a rat model of ACL reconstruction. | GHK-Cu | animal | 2015-07-01 |
| ANIMAL | evidence | Tripeptide-copper complex GHK-Cu (II) transiently improved healing outcome in a rat model of ACL reconstruction. | GHK | animal | 2015-07-01 |
| ANIMAL | evidence | Type-I interferons induce lung protease responses following respiratory syncytial virus infection via RIG-I-like receptors. | GHK | animal | 2015-01-01 |
| ANIMAL | evidence | Effects of topical copper tripeptide complex on wound healing in an irradiated rat model. | Copper tripeptide | animal | 2013-09-01 |
| ANIMAL | evidence | Effects of topical copper tripeptide complex on wound healing in an irradiated rat model. | GHK | Wound healing · animal | 2013-09-01 |
| ANIMAL | evidence | Biotinylated GHK peptide incorporated collagenous matrix: A novel biomaterial for dermal wound healing in rats. | GHK | animal | 2005-05-01 |
| ANIMAL | evidence | Initial upregulation of growth factors and inflammatory mediators during nerve regeneration in the presence of cell adhesive peptide-incorporated collagen tubes. | GHK | animal | 2005-03-01 |
| ANIMAL | evidence | 19F NMR studies of tryptophan/serum albumin binding. | GHK | animal | 2003-01-02 |
| ANIMAL | evidence | A K+ single channel and whole-cell clamp study on the effects of levocromakalim in guinea pig portal vein cells. | GHK | animal | 1998-09-01 |
| ANIMAL | evidence | Neuropeptide Y (NPY) or fragment NPY 13-36, but not NPY 18-36, inhibit retinotectal transfer in cane toads Bufo marinus. | GHK | animal | 1998-08-28 |
| ANIMAL | evidence | Simultaneous determination of glycyl-L-histidyl-L-lysine and its metabolite, L-histidyl-L-lysine, in rat plasma by high-performance liquid chromatography with post-column derivatization. | GHK | animal | 1997-04-25 |
| ANIMAL | evidence | Morphological features of bone healing under the effect of collagen-graft-glycosaminoglycan copolymer supplemented with the tripeptide Gly-His-Lys. | GHK | animal | 1996-08-01 |
| ANIMAL | evidence | Binding of the growth factor glycyl-L-histidyl-L-lysine by heparin. | GHK | animal | 1995-12-04 |
| ANIMAL | evidence | Effect of tripeptide-copper complexes on the process of skin wound healing and on cultured fibroblasts. | Gly-His-Lys-Cu | Skin appearance & aging · animal | 1995-11-01 |
| ANIMAL | evidence | Effect of neuropeptide-Y on tectal field potentials in the toad. | GHK | animal | 1995-01-09 |
| ANIMAL | evidence | Reactivity and the fate of some composite bioimplants based on collagen in connective tissue. | GHK | animal | 1995-01-01 |
| ANIMAL | evidence | In vivo stimulation of connective tissue accumulation by the tripeptide-copper complex glycyl-L-histidyl-L-lysine-Cu2+ in rat experimental wounds. | GHK | Skin appearance & aging · animal | 1993-11-01 |
| ANIMAL | evidence | In vivo stimulation of connective tissue accumulation by the tripeptide-copper complex glycyl-L-histidyl-L-lysine-Cu2+ in rat experimental wounds. | GHK-Cu | animal | 1993-11-01 |
| ANIMAL | evidence | ESR studies of the interaction of copper(II)GHK, histidine, and Ehrlich cells. | GHK | animal | 1989-03-01 |
| ANIMAL | evidence | Histocompatibility studies in a closely bred colony of dogs. 3. Genetic definition of the DL-A system of canine histocompatibility, with particular reference to the comparative immunogenicity of the major transplantable organs. | GHK | animal | 1971-11-01 |
| PRECLINICAL | evidence | Microenvironment-responsive injectable dynamic hydrogel for sequential antioxidant and tissue regeneration therapy of radiation-induced skin injury. | GHK | — | 2026-09-01 |
| PRECLINICAL | evidence | Microenvironment-responsive injectable dynamic hydrogel for sequential antioxidant and tissue regeneration therapy of radiation-induced skin injury. | glycyl-L-histidyl-L-lysine copper | — | 2026-09-01 |